Sparks, Alison

Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo

Böttger, A., Böttger, V., Sparks, A., Liu, W.-L., Howard, S. F., & Lane, D. P. (1997) · Current Biology

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 363

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

Stevenson, L. F., Sparks, A., Allende‐Vega, N., Xirodimas, D. P., Lane, D. P., & Saville, M. K. (2007) · The EMBO Journal

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 280

Regulation of p53 by the Ubiquitin-conjugating Enzymes UbcH5B/C in Vivo

Saville, M. K., Sparks, A., Xirodimas, D. P., Wardrop, J., Stevenson, L. F., Bourdon, J.-C., Woods, Y. L., & Lane, D. P. (2004) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 158

MdmX is a substrate for the deubiquitinating enzyme USP2a

Allende-Vega, N., Sparks, A., Lane, D. P., & Saville, M. K. (2010) · Oncogene

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 100