Dumont, Nancy

TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

Bhowmick, N. A., Chytil, A., Plieth, D., Gorska, A. E., Dumont, N., Shappell, S., Washington, M. K., Neilson, E. G., & Moses, H. L. (2004) · Science

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 1,401

Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

Corsello, S. M., Nagari, R. T., Spangler, R. D., Rossen, J., Kocak, M., Bryan, J. G., Humeidi, R., Peck, D., Wu, X., Tang, A. A., et al. (2020) · Nature Cancer

Computational Drug Discovery MethodsCancer Cells and Metastasis

Cited by 878

WRN helicase is a synthetic lethal target in microsatellite unstable cancers

Chan, E. M., Shibue, T., McFarland, J. M., Gaeta, B., Ghandi, M., Dumont, N., Gonzalez, A., McPartlan, J. S., Li, T., Zhang, Y., et al. (2019) · Nature

Genetic factors in colorectal cancerDNA Repair Mechanisms

Cited by 458

CD36 Repression Activates a Multicellular Stromal Program Shared by High Mammographic Density and Tumor Tissues

DeFilippis, R. A., Chang, H., Dumont, N., Rabban, J. T., Chen, Y.-Y., Fontenay, G. V., Berman, H. K., Gauthier, M. L., Zhao, J., Hu, D., et al. (2012) · Cancer Discovery

Digital Radiography and Breast ImagingCancer, Lipids, and Metabolism

Cited by 212

Breast Fibroblasts Modulate Early Dissemination, Tumorigenesis, and Metastasis through Alteration of Extracellular Matrix Characteristics

Dumont, N., Liu, B., DeFilippis, R. A., Chang, H., Rabban, J. T., Karnezis, A. N., Tjoe, J. A., Marx, J., Parvin, B., & Tlsty, T. D. (2013) · Neoplasia

Cancer Cells and MetastasisCellular Mechanics and Interactions

Cited by 192

Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

Sulahian, R., Kwon, J. J., Walsh, K. H., Pailler, E., Bosse, T. L., Thaker, M., Almanza, D., Dempster, J. M., Pan, J., Piccioni, F., et al. (2019) · Cell Reports

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 90