Sajjakulnukit, Peter

Cysteine depletion induces pancreatic tumor ferroptosis in mice

Badgley, M. A., Kremer, D. M., Maurer, H. C., DelGiorno, K. E., Lee, H.-J., Purohit, V., Sagalovskiy, I. R., Ma, A., Kapilian, J., Firl, C. E. M., et al. (2020) · Science

Ferroptosis and cancer prognosisCell death mechanisms and regulation

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Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer

Halbrook, C. J., Pontious, C., Kovalenko, I., Lapienyte, L., Dreyer, S., Lee, H.-J., Thurston, G., Zhang, Y., Lazarus, J., Sajjakulnukit, P., et al. (2019) · Cell Metabolism

Immune cells in cancerPancreatic and Hepatic Oncology Research

Cited by 419

HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron

Singhal, R., Mitta, S. R., Das, N. K., Kerk, S. A., Sajjakulnukit, P., Solanki, S., Andren, A., Kumar, R., Olive, K. P., Banerjee, R., et al. (2021) · Journal of Clinical Investigation

Ferroptosis and cancer prognosisCancer, Hypoxia, and Metabolism

Cited by 215

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context

Kerk, S. A., Lin, L., Myers, A. L., Sutton, D. J., Andren, A., Sajjakulnukit, P., Zhang, L., Zhang, Y., Jiménez, J. A., Nelson, B. S., et al. (2022) · eLife

Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 108

Hyaluronic acid fuels pancreatic cancer cell growth

Kim, P. K., Halbrook, C. J., Kerk, S. A., Radyk, M., Wisner, S., Kremer, D. M., Sajjakulnukit, P., Andren, A., Hou, S. W., Trivedi, A., et al. (2021) · eLife

Glycosylation and Glycoproteins ResearchCancer, Hypoxia, and Metabolism

Cited by 92

Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells

Halbrook, C. J., Thurston, G., Boyer, S., Anaraki, C., Jiménez, J. A., McCarthy, A., Steele, N. G., Kerk, S. A., Hong, H. S., Lin, L., et al. (2022) · Nature Cancer

Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 80

Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway

Boyer, S., Lee, H.-J., Steele, N., Zhang, L., Sajjakulnukit, P., Andren, A., Ward, M. H., Singh, R., Basrur, V., Zhang, Y., et al. (2022) · eLife

Immune cells in cancerPancreatic and Hepatic Oncology Research

Cited by 56

Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma

Xu, J., Reznik, E., Lee, H.-J., Gundem, G., Jonsson, P., Sarungbam, J., Bialik, A., Sanchez-Vega, F., Creighton, C. J., Hoekstra, J., et al. (2019) · eLife

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

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