Chen, Sam

The current landscape of nucleic acid therapeutics

Kulkarni, J. A., Witzigmann, D., Thomson, S. B., Chen, S., Leavitt, B. R., Cullis, P. R., & van der Meel, R. (2021) · Nature Nanotechnology

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 1,371

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

Belliveau, N. M., Huft, J., Lin, P. J., Chen, S., Leung, A. K., Leaver, T. J., Wild, A. W., Lee, J. B., Taylor, R. J., Tam, Y. K., et al. (2012) · Molecular Therapy - Nucleic Acids

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 685

On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA

Kulkarni, J. A., Darjuan, M. M., Mercer, J. E., Chen, S., van der Meel, R., Thewalt, J. L., Tam, Y. Y. C., & Cullis, P. R. (2018) · ACS Nano

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 663

Lipid nanoparticle technology for therapeutic gene regulation in the liver

Witzigmann, D., Kulkarni, J. A., Leung, J., Chen, S., Cullis, P. R., & van der Meel, R. (2020) · Advanced Drug Delivery Reviews

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 376

Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA

Chen, S., Tam, Y. Y. C., Lin, P. J. C., Sung, M. M. H., Tam, Y. K., & Cullis, P. R. (2016) · Journal of Controlled Release

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 366

Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems

Leung, A. K. K., Tam, Y. Y. C., Chen, S., Hafez, I. M., & Cullis, P. R. (2015) · The Journal of Physical Chemistry B

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 359

Advances in lipid nanoparticles for siRNA delivery

Tam, Y., Chen, S., & Cullis, P. (2013) · Pharmaceutics

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 229

Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration

Chen, S., Tam, Y. Y. C., Lin, P. J. C., Leung, A. K. K., Tam, Y. K., & Cullis, P. R. (2014) · Journal of Controlled Release

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 160