Lacaze, Paul

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Bellenguez, C., Küçükali, F., Jansen, I. E., Kleineidam, L., Moreno-Grau, S., Amin, N., Naj, A. C., Campos-Martin, R., Grenier-Boley, B., Andrade, V., et al. (2022) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 2,498

Blood DNA methylation as a potential biomarker of dementia: A systematic review

Fransquet, P. D., Lacaze, P., Saffery, R., McNeil, J., Woods, R., & Ryan, J. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchEpigenetics and DNA Methylation

Cited by 96

Phenotypic heterogeneity in dementia: a challenge for epidemiology and biomarker studies

Ryan, J., Fransquet, P., Wrigglesworth, J., & Lacaze, P. (2018) · Frontiers in Public Health

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 91

The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly

Pinese, M., Lacaze, P., Rath, E. M., Stone, A., Brion, M.-J., Ameur, A., Nagpal, S., Puttick, C., Husson, S., Degrave, D., et al. (2020) · Nature Communications

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 70

Blood DNA methylation signatures to detect dementia prior to overt clinical symptoms

Fransquet, P. D., Lacaze, P., Saffery, R., Phung, J., Parker, E., Shah, R., Murray, A., Woods, R. L., & Ryan, J. (2020) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Dementia and Cognitive Impairment ResearchEpigenetics and DNA Methylation

Cited by 36

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review

Huq, A. J., Fransquet, P., Laws, S. M., Ryan, J., Sebra, R., Masters, C. L., Winship, I. M., James, P. A., & Lacaze, P. (2019) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 35

DNA Methylation Analysis of Candidate Genes Associated with Dementia in Peripheral Blood

Fransquet, P. D., Lacaze, P., Saffery, R., Phung, J., Parker, E., Shah, R. C., Murray, A., Woods, R. L., & Ryan, J. (2020) · Epigenomics

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 25

Polygenic score modifies risk for Alzheimer's disease in APOE ε4 homozygotes at phenotypic extremes

Huq, A. J., Fulton‐Howard, B., Riaz, M., Laws, S., Sebra, R., Ryan, J., Alzheimer's Disease Genetics Consortium, Renton, A. E., Goate, A. M., Masters, C. L., et al. (2021) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 17