Khoutorsky, Arkady

Autism-related deficits via dysregulated eIF4E-dependent translational control

Gkogkas, C. G., Khoutorsky, A., Ran, I., Rampakakis, E., Nevarko, T., Weatherill, D. B., Vasuta, C., Yee, S., Truitt, M., Dallaire, P., et al. (2013) · Nature

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 522

Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes

Gkogkas, C. G., Khoutorsky, A., Cao, R., Jafarnejad, S. M., Prager-Khoutorsky, M., Giannakas, N., Kaminari, A., Fragkouli, A., Nader, K., Price, T. J., et al. (2014) · Cell Reports

Genetics and Neurodevelopmental DisordersRNA and protein synthesis mechanisms

Cited by 201

Microglia-mediated degradation of perineuronal nets promotes pain

Tansley, S., Gu, N., Guzmán, A. U., Cai, W., Wong, C., Lister, K. C., Muñoz-Pino, E., Yousefpour, N., Roome, R. B., Heal, J., et al. (2022) · Science

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 195

Metformin for treatment of fragile X syndrome and other neurological disorders

Gantois, I., Popic, J., Khoutorsky, A., & Sonenberg, N. (2019) · Annual Review of Medicine

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 87

Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain

Parisien, M., Samoshkin, A., Tansley, S. N., Piltonen, M. H., Martin, L. J., El-Hachem, N., Dagostino, C., Allegri, M., Mogil, J. S., Khoutorsky, A., et al. (2019) · Pain

Pain Mechanisms and TreatmentsPain Management and Treatment

Cited by 85

The gut microbiota promotes pain in fibromyalgia

Cai, W., Haddad, M., Haddad, R., Kesten, I., Hoffman, T., Laan, R., Westfall, S., Defaye, M., Abdullah, N. S., Wong, C., et al. (2025) · Neuron

Fibromyalgia and Chronic Fatigue Syndrome ResearchGut microbiota and health

Cited by 59

Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain

Lister, K. C., Wong, C., Uttam, S., Parisien, M., Stecum, P., Brown, N., Cai, W., Ho-Tieng, D., Hooshmandi, M., Gu, N., et al. (2026) · eLife

Pain Mechanisms and TreatmentsNeuroscience and Neuropharmacology Research

Cited by 2