George, Rani E.

Activating mutations in ALK provide a therapeutic target in neuroblastoma

George, R. E., Sanda, T., Hanna, M., Fröhling, S., II, W. L., Zhang, J., Ahn, Y., Zhou, W., London, W. B., McGrady, P., et al. (2008) · Nature

Neuroblastoma Research and TreatmentsNeurofibromatosis and Schwannoma Cases

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CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

Krajewska, M., Dries, R., Grassetti, A. V., Dust, S., Gao, Y., Huang, H., Sharma, B., Day, D. S., Kwiatkowski, N., Pomaville, M., et al. (2019) · Nature Communications

RNA Research and SplicingGenomics and Chromatin Dynamics

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Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK)

Powell, C. E., Gao, Y., Tan, L., Donovan, K. A., Nowak, R. P., Loehr, A., Bahcall, M., Fischer, E. S., Jänne, P. A., George, R. E., et al. (2018) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsLung Cancer Treatments and Mutations

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Zebrafish foxd3 is selectively required for neural crest specification, migration and survival

Stewart, R. A., Arduini, B. L., Berghmans, S., George, R. E., Kanki, J. P., Henion, P. D., & Look, A. T. (2006) · Developmental Biology

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

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Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma

Bayles, I., Krajewska, M., Pontius, W. D., Saiakhova, A., Morrow, J. J., Bartels, C., Lu, J., Faber, Z. J., Fedorov, Y., Hong, E. S., et al. (2019) · Journal of Clinical Investigation

Sarcoma Diagnosis and TreatmentChromatin Remodeling and Cancer

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