Aerts, Stein

Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation

Bravo González-Blas, C., Matetovici, I., Hillen, H., Taskiran, I. I., Vandepoel, R., Christiaens, V., Sansores-García, L., Verboven, E., Hulselmans, G., Poovathingal, S., et al. (2024) · Nature Cell Biology

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 85

Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic

Verfaillie, A., Svetlichnyy, D., Imrichova, H., Davie, K., Fiers, M., Kalender Atak, Z., Hulselmans, G., Christiaens, V., & Aerts, S. (2016) · Genome Research

Genomics and Chromatin DynamicsCancer-related Molecular Pathways

Cited by 82

Neuronal cell types in the fly: single-cell anatomy meets single-cell genomics

Bates, A. S., Janssens, J., Jefferis, G. S., & Aerts, S. (2019) · Current Opinion in Neurobiology

Neurobiology and Insect Physiology ResearchSingle-cell and spatial transcriptomics

Cited by 70

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation

Varum, S., Baggiolini, A., Zurkirchen, L., Atak, Z. K., Cantù, C., Marzorati, E., Bossart, R., Wouters, J., Häusel, J., Tuncer, E., et al. (2019) · Cell Stem Cell

Developmental Biology and Gene RegulationMelanoma and MAPK Pathways

Cited by 65

Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq

Mylka, V., Matetovici, I., Poovathingal, S., Aerts, J., Vandamme, N., Seurinck, R., Verstaen, K., Hulselmans, G., Van den Hoecke, S., Scheyltjens, I., et al. (2022) · Genome Biology

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 53

Interpretation of allele-specific chromatin accessibility using cell state–aware deep learning

Atak, Z. K., Taskiran, I. I., Demeulemeester, J., Flerin, C., Mauduit, D., Minnoye, L., Hulselmans, G., Christiaens, V., Ghanem, G.-E., Wouters, J., et al. (2021) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 48

Shared enhancer gene regulatory networks between wound and oncogenic programs

Floc'hlay, S., Balaji, R., Stanković, D., Christiaens, V. M., Bravo González-Blas, C., De Winter, S., Hulselmans, G. J., De Waegeneer, M., Quan, X., Koldere, D., et al. (2023) · eLife

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 27

Enhancer grammar of liver cell types and hepatocyte zonation states

González-Blas, C. B., Matetovici, I., Hillen, H., Taskiran, I. I., Vandepoel, R., Christiaens, V., Sansores-García, L., Verboven, E., Hulselmans, G., Poovathingal, S., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 5