Sturmlechner, Ines

Cellular senescence in renal ageing and disease

Sturmlechner, I., Durik, M., Sieben, C. J., Baker, D. J., & van Deursen, J. M. (2017) · Nature Reviews Nephrology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 345

p21 produces a bioactive secretome that places stressed cells under immunosurveillance

Sturmlechner, I., Zhang, C., Sine, C. C., van Deursen, E.-J., Jeganathan, K. B., Hamada, N., Grasic, J., Friedman, D., Stutchman, J. T., Can, I., et al. (2021) · Science

Cancer-related Molecular PathwaysImmune cells in cancer

Cited by 295

Two-Step Senescence-Focused Cancer Therapies

Sieben, C. J., Sturmlechner, I., van de Sluis, B., & van Deursen, J. M. (2018) · Trends in Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 222

Senescent alveolar macrophages promote early-stage lung tumorigenesis

Prieto, L. I., Sturmlechner, I., Graves, S. I., Zhang, C., Goplen, N. P., Yi, E. S., Sun, J., Li, H., & Baker, D. J. (2023) · Cancer Cell

Immune cells in cancerTelomeres, Telomerase, and Senescence

Cited by 212

p21 induces a senescence program and skeletal muscle dysfunction

Englund, D. A., Jolliffe, A., Aversa, Z., Zhang, X., Sturmlechner, I., Sakamoto, A. E., Zeidler, J. D., Warner, G. M., McNinch, C., White, T. A., et al. (2023) · Molecular Metabolism

Telomeres, Telomerase, and SenescenceMuscle Physiology and Disorders

Cited by 90

Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis

Childs, B. G., Zhang, C., Shuja, F., Sturmlechner, I., Trewartha, S., Velasco, R. F., Baker, D. J., Li, H., & van Deursen, J. M. (2021) · Nature Aging

Atherosclerosis and Cardiovascular DiseasesTelomeres, Telomerase, and Senescence

Cited by 76

Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies

Cherry, C., Andorko, J. I., Krishnan, K., Mejías, J. C., Nguyen, H. H., Stivers, K. B., Gray-Gaillard, E. F., Ruta, A., Han, J., Hamada, N., et al. (2023) · GeroScience

Telomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomics

Cited by 66