Sayes, Fadel

ESX secretion systems: mycobacterial evolution to counter host immunity

Gröschel, M. I., Sayes, F., Simeone, R., Majlessi, L., & Brosch, R. (2016) · Nature Reviews Microbiology

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 382

Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis

Supply, P., Marceau, M., Mangenot, S., Roche, D., Rouanet, C., Khanna, V., Majlessi, L., Criscuolo, A., Tap, J., Pawlik, A., et al. (2013) · Nature Genetics

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 305

ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis

Augenstreich, J., Arbues, A., Simeone, R., Haanappel, E., Wegener, A., Sayes, F., Le Chevalier, F., Chalut, C., Malaga, W., Guilhot, C., et al. (2017) · Cellular Microbiology

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 240

Disruption of the ESX‐5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

Bottai, D., Di Luca, M., Majlessi, L., Frigui, W., Simeone, R., Sayes, F., Bitter, W., Brennan, M. J., Leclerc, C., Batoni, G., et al. (2012) · Molecular Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 210

Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo

Simeone, R., Sayes, F., Song, O., Gröschel, M. I., Brodin, P., Brosch, R., & Majlessi, L. (2015) · PLOS Pathogens

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 198

Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection

Gröschel, M. I., Sayes, F., Shin, S. J., Frigui, W., Pawlik, A., Orgeur, M., Canetti, R., Honoré, N., Simeone, R., van der Werf, T. S., et al. (2017) · Cell Reports

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 125

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors

Sayes, F., Blanc, C., Ates, L. S., Deboosere, N., Orgeur, M., Le Chevalier, F., Gröschel, M. I., Frigui, W., Song, O.-R., Lo-Man, R., et al. (2018) · Cell Reports

Tuberculosis Research and EpidemiologyInfectious Diseases and Tuberculosis

Cited by 36