Smyth, Leon C. D.

Brain Pericytes As Mediators of Neuroinflammation

Rustenhoven, J., Jansson, D., Smyth, L. C., & Dragunow, M. (2017) · Trends in Pharmacological Sciences

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 371

Identification of direct connections between the dura and the brain

Smyth, L. C. D., Xu, D., Okar, S. V., Dykstra, T., Rustenhoven, J., Papadopoulos, Z., Bhasiin, K., Kim, M. W., Drieu, A., Mamuladze, T., et al. (2024) · Nature

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 264

PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia

Rustenhoven, J., Smith, A. M., Smyth, L. C., Jansson, D., Scotter, E. L., Swanson, M. E. V., Aalderink, M., Coppieters, N., Narayan, P., Handley, R., et al. (2018) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 155

Skull bone marrow channels as immune gateways to the central nervous system

Mazzitelli, J. A., Pulous, F. E., Smyth, L. C. D., Kaya, Z., Rustenhoven, J., Moskowitz, M. A., Kipnis, J., & Nahrendorf, M. (2023) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 116

Redefining CNS immune privilege

Smyth, L. C. D., & Kipnis, J. (2025) · Nature Reviews Immunology

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 80

An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination

Barclay, K. M., Abduljawad, N., Cheng, Z., Kim, M. W., Zhou, L., Yang, J., Rustenhoven, J., Mazzitelli, J. A., Smyth, L. C. D., Kapadia, D., et al. (2024) · Immunity

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 65

Isolation and culture of functional adult human neurons from neurosurgical brain specimens

Park, T. I.-H., Schweder, P., Lee, K., Dieriks, B. V., Jung, Y., Smyth, L., Rustenhoven, J., Mee, E., Heppner, P., Turner, C., et al. (2020) · Brain Communications

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 28

The amyotrophic lateral sclerosis-linked protein TDP-43 regulates interleukin-6 cytokine production by human brain pericytes

Scotter, E. L., Cao, M. C., Jansson, D., Rustenhoven, J., Smyth, L. C. D., Aalderink, M. C., Siemens, A., Fan, V., Wu, J., Mee, E. W., et al. (2022) · Molecular and Cellular Neuroscience

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 13