Reijns, Martin A. M.

cGAS surveillance of micronuclei links genome instability to innate immunity

Mackenzie, K. J., Carroll, P., Martin, C.-A., Murina, O., Fluteau, A., Simpson, D. J., Olova, N., Sutcliffe, H., Rainger, J. K., Leitch, A., et al. (2017) · Nature

interferon and immune responsesImmune Response and Inflammation

Cited by 1,752

Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

Reijns, M. A. M., Rabe, B., Rigby, R. E., Mill, P., Astell, K. R., Lettice, L. A., Boyle, S., Leitch, A., Keighren, M., Kilanowski, F., et al. (2012) · Cell

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 466

Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response

Mackenzie, K. J., Carroll, P., Lettice, L., Tarnauskaitė, Ž., Reddy, K., Dix, F., Revuelta, A., Abbondati, E., Rigby, R. E., Rabe, B., et al. (2016) · The EMBO Journal

interferon and immune responsesSystemic Lupus Erythematosus Research

Cited by 248

Lagging-strand replication shapes the mutational landscape of the genome

Reijns, M. A. M., Kemp, H., Ding, J., Marion de Procé, S., Jackson, A. P., & Taylor, M. S. (2015) · Nature

DNA Repair MechanismsEvolution and Genetic Dynamics

Cited by 241

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

Uggenti, C., Lepelley, A., Depp, M., Badrock, A. P., Rodero, M. P., El-Daher, M.-T., Rice, G. I., Dhir, S., Wheeler, A. P., Dhir, A., et al. (2020) · Nature Genetics

interferon and immune responsesInflammasome and immune disorders

Cited by 192

PCNA directs type 2 RNase H activity on DNA replication and repair substrates

Bubeck, D., Reijns, M. A. M., Graham, S. C., Astell, K. R., Jones, E. Y., & Jackson, A. P. (2011) · Nucleic Acids Research

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 144

In silico protein interaction screening uncovers DONSON’s role in replication initiation

Lim, Y., Tamayo-Orrego, L., Schmid, E., Tarnauskaite, Z., Kochenova, O. V., Gruar, R., Muramatsu, S., Lynch, L., Schlie, A. V., Carroll, P. L., et al. (2023) · Science

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 112

DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes

Giordano, A. M. S., Luciani, M., Gatto, F., Abou Alezz, M., Beghè, C., Della Volpe, L., Migliara, A., Valsoni, S., Genua, M., Dzieciatkowska, M., et al. (2022) · Journal of Experimental Medicine

interferon and immune responsesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 76

Genome-wide mapping of embedded ribonucleotides and other noncanonical nucleotides using emRiboSeq and EndoSeq

Ding, J., Taylor, M. S., Jackson, A. P., & Reijns, M. A. M. (2015) · Nature Protocols

DNA Repair MechanismsGenomics and Phylogenetic Studies

Cited by 47