Chiang, John Y.L.

Bile acid signaling in metabolic disease and drug therapy

Li, T., & Chiang, J. Y. L. (2014) · Pharmacological Reviews

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 935

Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy

Chiang, J. Y. L., & Ferrell, J. M. (2020) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 580

Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism

Pathak, P., Xie, C., Nichols, R. G., Ferrell, J. M., Boehme, S., Krausz, K. W., Patterson, A. D., Gonzalez, F. J., & Chiang, J. Y. L. (2018) · Hepatology

Drug Transport and Resistance MechanismsGut microbiota and health

Cited by 567

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

Kong, B., Wang, L., Chiang, J. Y. L., Zhang, Y., Klaassen, C. D., & Guo, G. L. (2012) · Hepatology

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 456

Interactive relationships between intestinal flora and bile acids

Guo, X., Okpara, E. S., Hu, W., Yan, C., Wang, Y., Liang, Q., Chiang, J. Y. L., & Han, S. (2022) · International Journal of Molecular Sciences

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 206

Nuclear receptors in bile acid metabolism

Li, T., & Chiang, J. Y. L. (2013) · Drug Metabolism Reviews

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 176

Understanding bile acid signaling in diabetes: From pathophysiology to therapeutic targets

Ferrell, J. M., & Chiang, J. Y. L. (2019) · Diabetes & Metabolism Journal

Drug Transport and Resistance MechanismsGut microbiota and health

Cited by 139

Regulation of cholesterol 7 alpha-hydroxylase in the liver. Purification of cholesterol 7 alpha-hydroxylase and the immunochemical evidence for the induction of cholesterol 7 alpha-hydroxylase by cholestyramine and circadian rhythm.

Chiang, J. Y., Miller, W. F., & Lin, G. M. (1990) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismPharmacogenetics and Drug Metabolism

Cited by 123

Nuclear receptor-mediated repression of human cholesterol 7α-hydroxylase gene transcription by bile acids

Chen, W., Owsley, E., Yang, Y., Stroup, D., & Chiang, J. Y. L. (2001) · Journal of Lipid Research

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 112

Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders

Ferrell, J. M., Boehme, S., Li, F., & Chiang, J. Y. L. (2016) · Journal of Lipid Research

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 112

Deficiency of Both Farnesoid X Receptor and Takeda G Protein–Coupled Receptor 5 Exacerbated Liver Fibrosis in Mice

Ferrell, J. M., Pathak, P., Boehme, S., Gilliland, T., & Chiang, J. Y. L. (2019) · Hepatology

Drug Transport and Resistance MechanismsLiver physiology and pathology

Cited by 65