Winkel, Frederike

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

Casarotto, P. C., Girych, M., Fred, S. M., Kovaleva, V., Moliner, R., Enkavi, G., Biojone, C., Cannarozzo, C., Sahu, M. P., Kaurinkoski, K., et al. (2021) · Cell

Treatment of Major DepressionNerve injury and regeneration

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iPlasticity: Induced juvenile‐like plasticity in the adult brain as a mechanism of antidepressants

Umemori, J., Winkel, F., Didio, G., Llach Pou, M., & Castrén, E. (2018) · Psychiatry and Clinical Neurosciences

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

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Chondroitinase and Antidepressants Promote Plasticity by Releasing TRKB from Dephosphorylating Control of PTPσ in Parvalbumin Neurons

Lesnikova, A., Casarotto, P. C., Fred, S. M., Voipio, M., Winkel, F., Steinzeig, A., Antila, H., Umemori, J., Biojone, C., & Castrén, E. (2021) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

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Pharmacological and optical activation of TrkB in Parvalbumin interneurons regulate intrinsic states to orchestrate cortical plasticity

Winkel, F., Ryazantseva, M., Voigt, M. B., Didio, G., Lilja, A., Llach Pou, M., Steinzeig, A., Harkki, J., Englund, J., Khirug, S., et al. (2021) · Molecular Psychiatry

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

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Kainate Receptor Auxiliary Subunit NETO2-Related Cued Fear Conditioning Impairments Associate with Defects in Amygdala Development and Excitability

Mennesson, M., Orav, E., Gigliotta, A., Kulesskaya, N., Saarnio, S., Kirjavainen, A., Kesaf, S., Winkel, F., Llach Pou, M., Umemori, J., et al. (2020) · eneuro

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