McMahon, Steven B.

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

Wise, D. R., DeBerardinis, R. J., Mancuso, A., Sayed, N., Zhang, X.-Y., Pfeiffer, H. K., Nissim, I., Daikhin, E., Yudkoff, M., McMahon, S. B., et al. (2008) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 2,001

Acetylation of the p53 DNA-binding domain regulates apoptosis induction.

Sykes, S. M., Mellert, H. S., Holbert, M. A., Li, K., Marmorstein, R., Lane, W. S., & McMahon, S. B. (2006) · Molecular Cell

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 752

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

McMahon, S. B., Van Buskirk, H. A., Dugan, K. A., Copeland, T. D., & Cole, M. D. (1998) · Cell

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 693

The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc

McMahon, S. B., Wood, M. A., & Cole, M. D. (2000) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 494

The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression

Zhang, X.-Y., Varthi, M., Sykes, S. M., Phillips, C., Warzecha, C., Zhu, W., Wyce, A., Thorne, A. W., Berger, S. L., & McMahon, S. B. (2008) · Molecular Cell

Genomics and Chromatin DynamicsUbiquitin and proteasome pathways

Cited by 427

USP22 regulates oncogenic signaling pathways to drive lethal cancer progression

Schrecengost, R. S., Dean, J. L., Goodwin, J. F., Schiewer, M. J., Urban, M. W., Stanek, T. J., Sussman, R. T., Hicks, J. L., Birbe, R. C., Draganova-Tacheva, R. A., et al. (2014) · Cancer Research

Ubiquitin and proteasome pathwaysProstate Cancer Treatment and Research

Cited by 126

The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)

Sussman, R. T., Stanek, T. J., Esteso, P., Gearhart, J. D., Knudsen, K. E., & McMahon, S. B. (2013) · Journal of Biological Chemistry

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 91