Funahashi, Yasuhiro

Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage.

Yamamoto, Y., Matsui, J., Matsushima, T., Obaishi, H., Miyazaki, K., Nakamura, K., Tohyama, O., Semba, T., Yamaguchi, A., Hoshi, S., et al. (2014) · Vascular Cell

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 507

Antitumor activity of lenvatinib (e7080): an angiogenesis inhibitor that targets multiple receptor tyrosine kinases in preclinical human thyroid cancer models.

Tohyama, O., Matsui, J., Kodama, K., Hata-Sugi, N., Kimura, T., Okamoto, K., Minoshima, Y., Iwata, M., & Funahashi, Y. (2014) · Journal of Thyroid Research

Thyroid Cancer Diagnosis and TreatmentAngiogenesis and VEGF in Cancer

Cited by 475

A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

Kitamura, T., Kitamura, Y. I., Funahashi, Y., Shawber, C. J., Castrillon, D. H., Kollipara, R., DePinho, R. A., Kitajewski, J., & Accili, D. (2007) · Journal of Clinical Investigation

Muscle Physiology and DisordersFOXO transcription factor regulation

Cited by 285

Distinct binding mode of multikinase inhibitor lenvatinib revealed by biochemical characterization.

Okamoto, K., Ikemori-Kawada, M., Jestel, A., von König, K., Funahashi, Y., Matsushima, T., Tsuruoka, A., Inoue, A., & Matsui, J. (2015) · ACS Medicinal Chemistry Letters

Angiogenesis and VEGF in CancerEnzyme Structure and Function

Cited by 285

Abstract 3266: Antitumor activity of a combination of lenvatinib mesilate, ifosfamide, and etoposide against human pediatric osteosarcoma cell lines

Matsuki, M., Okamoto, K., Dezso, Z., Agoulnik, S. I., Funahashi, Y., & Matsui, J. (2016) · Cancer Research

Sarcoma Diagnosis and TreatmentBone Tumor Diagnosis and Treatments

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