Cheng, Tzuling

Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey

Kim, S. C., Sprung, R., Chen, Y., Xu, Y., Ball, H., Pei, J., Cheng, T., Kho, Y., Xiao, H., Xiao, L., et al. (2006) · Molecular Cell

Advanced Proteomics Techniques and ApplicationsUbiquitin and proteasome pathways

Cited by 1,487

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

DeBerardinis, R. J., & Cheng, T. (2010) · Oncogene

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 1,365

Reductive carboxylation supports growth in tumour cells with defective mitochondria

Mullen, A. R., Wheaton, W. W., Jin, E. S., Chen, P.-H., Sullivan, L. B., Cheng, T., Yang, Y., Linehan, W. M., Chandel, N. S., & DeBerardinis, R. J. (2012) · Nature

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

Cited by 1,328

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

Cheng, T., Sudderth, J., Yang, C., Mullen, A. R., Jin, E. S., Matés, J. M., & DeBerardinis, R. J. (2011) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 475

A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma

Wallace, E. M., Rizzi, J. P., Han, G., Wehn, P. M., Cao, Z., Du, X., Cheng, T., Czerwinski, R. M., Dixon, D. D., Goggin, B. S., et al. (2016) · Cancer Research

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

Cited by 336

ARC-20: a Phase 1 dose-escalation and dose-expansion study to investigate the safety, tolerability, and pharmacology of HIF-2α inhibitor AB521 monotherapy in patients with clear cell renal cell carcinoma and other solid tumors

Choueiri, T. K., Garmezy, B., Paterson, E., Ghasemi, M., Cheng, T., Foster, P. G., Hauke, R. J., & Patnaik, A. (2023) · Journal of Clinical Oncology

Renal cell carcinoma treatmentCancer, Hypoxia, and Metabolism

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