Anastopoulos, Ioannis N.

Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

Shaffer, S. M., Dunagin, M. C., Torborg, S. R., Torre, E. A., Emert, B., Krepler, C., Beqiri, M., Sproesser, K., Brafford, P. A., Xiao, M., et al. (2017) · Nature

Cancer Cells and MetastasisSingle-cell and spatial transcriptomics

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BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers

Maxwell, K. N., Wubbenhorst, B., Wenz, B. M., De Sloover, D., Pluta, J., Emery, L., Barrett, A., Kraya, A. A., Anastopoulos, I. N., Yu, S., et al. (2017) · Nature Communications

BRCA gene mutations in cancerPARP inhibition in cancer therapy

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VEGA is an interpretable generative model for inferring biological network activity in single-cell transcriptomics

Seninge, L., Anastopoulos, I., Ding, H., & Stuart, J. (2021) · Nature Communications

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

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