Smeal, Tod

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

Hibi, M., Lin, A., Smeal, T., Minden, A., & Karin, M. (1993) · Genes & Development

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 1,886

Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction

Yang-Yen, H.-F., Chambard, J.-C., Sun, Y.-L., Smeal, T., Schmidt, T. J., Drouin, J., & Karin, M. (1990) · Cell

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 1,553

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

Angel, P., Hattori, K., Smeal, T., & Karin, M. (1988) · Cell

Protein Kinase Regulation and GTPase SignalingGenomics and Chromatin Dynamics

Cited by 1,239

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

Smeal, T., Binetruy, B., Mercola, D. A., Birrer, M., & Karin, M. (1991) · Nature

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 789

Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae

Smeal, T., Claus, J., Kennedy, B., Cole, F., & Guarente, L. (1996) · Cell

Genetics, Aging, and Longevity in Model OrganismsGenomics and Chromatin Dynamics

Cited by 308

PAK4 mediates morphological changes through the regulation of GEF-H1

Callow, M. G., Zozulya, S., Gishizky, M. L., Jallal, B., & Smeal, T. (2005) · Journal of Cell Science

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 169

Onvansertib in Combination with FOLFIRI and Bevacizumab in Second-Line Treatment of KRAS -Mutant Metastatic Colorectal Cancer: A Phase Ib Clinical Study

Ahn, D. H., Barzi, A., Ridinger, M., Samuëlsz, E., Subramanian, R. A., Wu, C.-C., Croucher, P. J. P., Smeal, T., Kabbinavar, F. F., & Lenz, H.-J. (2024) · Clinical Cancer Research

Colorectal Cancer Treatments and StudiesLung Cancer Treatments and Mutations

Cited by 49