Liu, Zhandong

Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease

Roy, E. R., Wang, B., Wan, Y.-W., Chiu, G., Cole, A., Yin, Z., Propson, N. E., Xu, Y., Jankowsky, J. L., Liu, Z., et al. (2020) · Journal of Clinical Investigation

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease

Litvinchuk, A., Wan, Y.-W., Swartzlander, D. B., Chen, F., Cole, A., Propson, N. E., Wang, Q., Zhang, B., Liu, Z., & Zheng, H. (2018) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 523

Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia

Ye, J., Fan, J., Venneti, S., Wan, Y.-W., Pawel, B. R., Zhang, J., Finley, L. W. S., Lu, C., Lindsten, T., Cross, J. R., et al. (2014) · Cancer Discovery

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 452

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Sieberts, S. K., Perumal, T. M., Carrasquillo, M. M., Allen, M., Reddy, J. S., Hoffman, G. E., Dang, K. K., Calley, J., Ebert, P. J., Eddy, J., et al. (2020) · Scientific Data

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 318

Tau Activates Transposable Elements in Alzheimer’s Disease

Guo, C., Jeong, H.-H., Hsieh, Y.-C., Klein, H.-U., Bennett, D. A., De Jager, P. L., Liu, Z., & Shulman, J. M. (2018) · Cell Reports

Alzheimer's disease research and treatmentsChromosomal and Genetic Variations

Cited by 315

Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models

Wan, Y.-W., Al-Ouran, R., Mangleburg, C. G., Perumal, T. M., Lee, T. V., Allison, K., Swarup, V., Funk, C. C., Gaiteri, C., Allen, M., et al. (2020) · Cell Reports

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 295

TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading

Martini-Stoica, H., Cole, A. L., Swartzlander, D. B., Chen, F., Wan, Y.-W., Bajaj, L., Bader, D. A., Lee, V. M. Y., Trojanowski, J. Q., Liu, Z., et al. (2018) · Journal of Experimental Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 253

Tau-mediated disruption of the spliceosome triggers cryptic rna splicing and neurodegeneration in Alzheimer's Disease

Hsieh, Y.-C., Guo, C., Yalamanchili, H. K., Abreha, M., Al-Ouran, R., Li, Y., Dammer, E. B., Lah, J. J., Levey, A. I., Bennett, D. A., et al. (2019) · Cell Reports

Alzheimer's disease research and treatmentsRNA Research and Splicing

Cited by 196

A cross-species proteomic map reveals neoteny of human synapse development

Wang, L., Pang, K., Zhou, L., Cebrián-Silla, A., González-Granero, S., Wang, S., Bi, Q., White, M. L., Ho, B., Li, J., et al. (2023) · Nature

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 82

A cross-species proteomic map reveals neoteny of human synapse development

Wang, L., Pang, K., Zhou, L., Cebrián-Silla, A., González-Granero, S., Wang, S., Bi, Q., White, M. L., Ho, B., Li, J., et al. (2022) · Nature

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 82

Integrated analysis of the aging brain transcriptome and proteome in tauopathy

Mangleburg, C. G., Wu, T., Yalamanchili, H. K., Guo, C., Hsieh, Y.-C., Duong, D. M., Dammer, E. B., De Jager, P. L., Seyfried, N. T., Liu, Z., et al. (2020) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Benchmarked approaches for reconstruction of in vitro cell lineages and in silico models of C. elegans and M. musculus developmental trees

Gong, W., Granados, A. A., Hu, J., Jones, M. G., Raz, O., Salvador-Martínez, I., Zhang, H., Chow, K.-H. K., Kwak, I.-Y., Retkute, R., et al. (2021) · Cell Systems

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 62

A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach

Rousseaux, M. W. C., Vázquez-Vélez, G. E., Al-Ramahi, I., Jeong, H.-H., Bajić, A., Revelli, J.-P., Ye, H., Phan, E. T., Deger, J. M., Perez, A. M., et al. (2018) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome

Veeraragavan, S., Wan, Y.-W., Connolly, D. R., Hamilton, S. M., Ward, C. S., Soriano, S., Pitcher, M. R., McGraw, C. M., Huang, S. G., Green, J. R., et al. (2016) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

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AI-MARRVEL — A Knowledge-Driven AI System for Diagnosing Mendelian Disorders

Mao, D., Liu, C., Wang, L., AI-Ouran, R., Deisseroth, C., Pasupuleti, S., Kim, S. Y., Li, L., Rosenfeld, J. A., Meng, L., et al. (2024) · NEJM AI

Genomics and Rare DiseasesArtificial Intelligence in Healthcare and Education

Cited by 51

Evolutionarily conserved regulators of tau identify targets for new therapies

Kim, J., de Haro, M., Al-Ramahi, I., Garaicoechea, L. L., Jeong, H.-H., Sonn, J. Y., Tadros, B., Liu, Z., Botas, J., & Zoghbi, H. Y. (2023) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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A portal to visualize transcriptome profiles in mouse models of neurological disorders

Al-Ouran, R., Wan, Y.-W., Mangleburg, C. G., Lee, T. V., Allison, K., Shulman, J. M., & Liu, Z. (2019) · Genes

Bioinformatics and Genomic NetworksAlzheimer's disease research and treatments

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Factors associated with postpartum depression symptoms following antepartum hospitalization

Goulding, A. N., Palacios, D., Aras, S., Chen, H., Pasupuleti, S., Toscano, M., Cirino, N., Christie, I. C., Liu, Z., Miller, E. S., et al. (2026) · Pregnancy

Maternal Mental Health During Pregnancy and PostpartumMaternal and Perinatal Health Interventions

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