Krimpenfort, Paul

cGAS–STING drives ageing-related inflammation and neurodegeneration

Gulen, M. F., Samson, N., Keller, A., Schwabenland, M., Liu, C., Glück, S., Thacker, V. V., Favre, L., Mangeat, B., Kroese, L. J., et al. (2023) · Nature

Neuroinflammation and Neurodegeneration Mechanismsinterferon and immune responses

Cited by 1,104

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis

Derksen, P. W. B., Liu, X., Saridin, F., van der Gulden, H., Zevenhoven, J., Evers, B., van Beijnum, J. R., Griffioen, A. W., Vink, J., Krimpenfort, P., et al. (2006) · Cancer Cell

Cancer Cells and MetastasisBreast Lesions and Carcinomas

Cited by 591

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

Krimpenfort, P., Quon, K. C., Mooi, W. J., Loonstra, A., & Berns, A. (2001) · Nature

Cancer-related Molecular PathwaysMelanoma and MAPK Pathways

Cited by 568

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo

Mainardi, S., Mulero-Sánchez, A., Prahallad, A., Germano, G., Bosma, A., Krimpenfort, P., Lieftink, C., Steinberg, J. D., de Wit, N., Gonçalves-Ribeiro, S., et al. (2018) · Nature Medicine

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 320

p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a

Krimpenfort, P., IJpenberg, A., Song, J.-Y., van der Valk, M., Nawijn, M., Zevenhoven, J., & Berns, A. (2007) · Nature

Cancer-related Molecular PathwaysChromatin Remodeling and Cancer

Cited by 269

DCC expression by neurons regulates synaptic plasticity in the adult brain

Horn, K. E., Glasgow, S. D., Gobert, D., Bull, S.-J., Luk, T., Girgis, J., Tremblay, M.-E., McEachern, D., Bouchard, J.-F., Haber, M., et al. (2013) · Cell Reports

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 147

DCC Receptors Drive Prefrontal Cortex Maturation by Determining Dopamine Axon Targeting in Adolescence

Reynolds, L. M., Pokinko, M., Torres-Berrío, A., Cuesta, S., Lambert, L. C., Del Cid Pellitero, E., Wodzinski, M., Manitt, C., Krimpenfort, P., Kolb, B., et al. (2018) · Biological Psychiatry

Axon Guidance and Neuronal SignalingNeurotransmitter Receptor Influence on Behavior

Cited by 129

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients

Manitt, C., Eng, C., Pokinko, M., Ryan, R. T., Torres-Berrío, A., Lopez, J. P., Yogendran, S. V., Daubaras, M. J. J., Grant, A., Schmidt, E. R. E., et al. (2013) · Translational Psychiatry

Neurotransmitter Receptor Influence on BehaviorAxon Guidance and Neuronal Signaling

Cited by 125