Pagliarini, Raymond

Project DRIVE: a compendium of cancer dependencies and synthetic lethal relationships uncovered by large-scale, deep RNAi screening

McDonald, E. R., de Weck, A., Schlabach, M. R., Billy, E., Mavrakis, K. J., Hoffman, G. R., Belur, D., Castelletti, D., Frias, E., Gampa, K., et al. (2017) · Cell

Chromatin Remodeling and CancerCancer Genomics and Diagnostics

Cited by 658

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Mavrakis, K. J., McDonald, E. R., Schlabach, M. R., Billy, E., Hoffman, G. R., deWeck, A., Ruddy, D. A., Venkatesan, K., Yu, J., McAllister, G., et al. (2016) · Science

Cancer-related gene regulationRNA modifications and cancer

Cited by 607

A Genetic Screen in Drosophila for Metastatic Behavior

Pagliarini, R. A., & Xu, T. (2003) · Science

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 543

Loss of Cell Polarity Drives Tumor Growth and Invasion through JNK Activation in Drosophila

Igaki, T., Pagliarini, R. A., & Xu, T. (2006) · Current Biology

Protein Kinase Regulation and GTPase SignalingHippo pathway signaling and YAP/TAZ

Cited by 370

IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism

Grassian, A. R., Parker, S. J., Davidson, S. M., Divakaruni, A. S., Green, C. R., Zhang, X., Slocum, K. L., Pu, M., Lin, F., Vickers, C., et al. (2014) · Cancer Research

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

Cited by 280

PIK3CA Mutation Uncouples Tumor Growth and Cyclin D1 Regulation from MEK/ERK and Mutant KRAS Signaling

Halilovic, E., She, Q.-B., Ye, Q., Pagliarini, R., Sellers, W. R., Solit, D. B., & Rosen, N. (2010) · Cancer Research

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 168

Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth

Chen, J., Chung, F., Yang, G., Pu, M., Gao, H., Jiang, W., Yin, H., Capka, V., Kasibhatla, S., Laffitte, B., et al. (2013) · Oncotarget

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 82