Sundar, Isaac K.

Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in mouse lung

Lerner, C. A., Sundar, I. K., Yao, H., Gerloff, J., Ossip, D. J., McIntosh, S., Robinson, R., & Rahman, I. (2015) · PLOS ONE

Smoking Behavior and CessationAntioxidant Activity and Oxidative Stress

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Redox regulation of SIRT1 in inflammation and cellular senescence

Hwang, J.-W., Yao, H., Caito, S., Sundar, I. K., & Rahman, I. (2013) · Free Radical Biology and Medicine

Sirtuins and Resveratrol in MedicineNitric Oxide and Endothelin Effects

Cited by 503

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

Yao, H., Chung, S., Hwang, J.-W., Rajendrasozhan, S., Sundar, I. K., Dean, D. A., McBurney, M. W., Guarente, L., Gu, W., Rönty, M., et al. (2012) · Journal of Clinical Investigation

Sirtuins and Resveratrol in MedicineChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 358

Impaired mitophagy leads to cigarette smoke stress‐induced cellular senescence: implications for chronic obstructive pulmonary disease

Ahmad, T., Sundar, I. K., Lerner, C. A., Gerloff, J., Tormos, A. M., Yao, H., & Rahman, I. (2015) · The FASEB Journal

Autophagy in Disease and TherapyTelomeres, Telomerase, and Senescence

Cited by 264

SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism

Yao, H., Sundar, I. K., Ahmad, T., Lerner, C., Gerloff, J., Friedman, A. E., Phipps, R. P., Sime, P. J., McBurney, M. W., Guarente, L., et al. (2014) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Sirtuins and Resveratrol in MedicineChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 104

Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease

Ahmad, T., Sundar, I. K., Tormos, A. M., Lerner, C. A., Gerloff, J., Yao, H., & Rahman, I. (2017) · American Journal of Respiratory Cell and Molecular Biology

Telomeres, Telomerase, and SenescenceSirtuins and Resveratrol in Medicine

Cited by 67

Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema

Rashid, K., Sundar, I. K., Gerloff, J., Li, D., & Rahman, I. (2018) · Scientific Reports

Chronic Obstructive Pulmonary Disease (COPD) ResearchTelomeres, Telomerase, and Senescence

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