Helquist, Paul

Structural insights into HDAC6 tubulin deacetylation and its selective inhibition

Miyake, Y., Keusch, J. J., Wang, L., Saito, M., Hess, D., Wang, X., Melancon, B. J., Helquist, P., Gut, H., & Matthias, P. (2016) · Nature Chemical Biology

Histone Deacetylase Inhibitors ResearchEnzyme Structure and Function

Cited by 315

Inhibition of histone deacetylases: A pharmacological approach to the treatment of non-cancer disorders

Wiech, N., Fisher, J., Helquist, P., & Wiest, O. (2009) · Current Topics in Medicinal Chemistry

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 66

Microsecond timescale MD simulations at the transition state of Pm HMGR predict remote allosteric residues

Quinn, T. R., Steussy, C. N., Haines, B. E., Lei, J., Wang, W., Sheong, F. K., Stauffacher, C. V., Huang, X., Norrby, P.-O., Helquist, P., et al. (2021) · Chemical Science

Protein Structure and DynamicsPhysical Organic Chemistry and Reaction Kinetics

Cited by 12