Wu, Xiwei

Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis

Zhou, W., Fong, M. Y., Min, Y., Somlo, G., Liu, L., Palomares, M. R., Yu, Y., Chow, A., O’Connor, S. T. F., Chin, A. R., et al. (2014) · Cancer Cell

MicroRNA in disease regulationExtracellular vesicles in disease

Cited by 1,476

Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

Fong, M. Y., Zhou, W., Liu, L., Alontaga, A. Y., Chandra, M., Ashby, J., Chow, A., O’Connor, S. T. F., Li, S., Chin, A. R., et al. (2015) · Nature Cell Biology

MicroRNA in disease regulationCancer, Hypoxia, and Metabolism

Cited by 1,118

Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

Huang, H., Weng, H., Zhou, K., Wu, T., Zhao, B. S., Sun, M., Chen, Z., Deng, X., Xiao, G., Auer, F., et al. (2019) · Nature

RNA modifications and cancerEpigenetics and DNA Methylation

Cited by 677

Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors

Wang, X., Wang, Y., Wu, X., Wang, J., Wang, Y., Qiu, Z., Chang, T., Huang, H., Lin, R.-J., & Yee, J.-K. (2015) · Nature Biotechnology

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 442

Genomic mapping of 5-hydroxymethylcytosine in the human brain

Jin, S.-G., Wu, X., Li, A. X., & Pfeifer, G. P. (2011) · Nucleic Acids Research

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 375

Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration

Jin, S.-G., Zhang, Z.-M., Dunwell, T. L., Harter, M. R., Wu, X., Johnson, J., Li, Z., Liu, J., Szabó, P. E., Lu, Q., et al. (2016) · Cell Reports

Epigenetics and DNA MethylationDNA and Nucleic Acid Chemistry

Cited by 138

Deleterious effects of endocrine disruptors are corrected in the mammalian germline by epigenome reprogramming

Iqbal, K., Tran, D. A., Li, A. X., Warden, C., Bai, A. Y., Singh, P., Wu, X., Pfeifer, G. P., & Szabó, P. E. (2015) · Genome Biology

Epigenetics and DNA MethylationEffects and risks of endocrine disrupting chemicals

Cited by 137

Acquired resistance to KRAS G12C small-molecule inhibitors via genetic/nongenetic mechanisms in lung cancer

Mohanty, A., Nam, A., Srivastava, S., Jones, J., Lomenick, B., Singhal, S. S., Guo, L., Cho, H., Li, A., Behal, A., et al. (2023) · Science Advances

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

Cited by 79

Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization

Tommasi, S., Zheng, A., Weninger, A., Bates, S. E., Li, X. A., Wu, X., Hollstein, M., & Besaratinia, A. (2013) · Nucleic Acids Research

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 45

Rlip depletion prevents spontaneous neoplasia in TP53 null mice

Awasthi, S., Tompkins, J., Singhal, J., Riggs, A. D., Yadav, S., Wu, X., Singh, S., Warden, C., Liu, Z., Wang, J., et al. (2018) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 33