Hare, Stephen

Retroviral intasome assembly and inhibition of DNA strand transfer

Hare, S., Gupta, S. S., Valkov, E., Engelman, A., & Cherepanov, P. (2010) · Nature

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 678

Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance

Hare, S., Vos, A. M., Clayton, R. F., Thuring, J. W., Cummings, M. D., & Cherepanov, P. (2010) · Proceedings of the National Academy of Sciences

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 305

The mechanism of retroviral integration from X-ray structures of its key intermediates

Maertens, G. N., Hare, S., & Cherepanov, P. (2010) · Nature

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 296

Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)

Hare, S., Smith, S. J., Métifiot, M., Jaxa-Chamiec, A., Pommier, Y., Hughes, S. H., & Cherepanov, P. (2011) · Molecular Pharmacology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 264

A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75

Hare, S., Shun, M.-C., Gupta, S. S., Valkov, E., Engelman, A., & Cherepanov, P. (2009) · PLoS Pathogens

Virus-based gene therapy researchHIV Research and Treatment

Cited by 166

3′‐Processing and strand transfer catalysed by retroviral integrase in crystallo

Hare, S., Maertens, G. N., & Cherepanov, P. (2012) · The EMBO Journal

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 153

Structural basis for retroviral integration into nucleosomes

Maskell, D. P., Renault, L., Serrao, E., Lesbats, P., Matadeen, R., Hare, S., Lindemann, D., Engelman, A. N., Costa, A., & Cherepanov, P. (2015) · Nature

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 138

Functional and structural characterization of the integrase from the prototype foamy virus

Valkov, E., Gupta, S. S., Hare, S., Helander, A., Roversi, P., McClure, M., & Cherepanov, P. (2009) · Nucleic Acids Research

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 130

Structural Basis for Functional Tetramerization of Lentiviral Integrase

Hare, S., Di Nunzio, F., Labeja, A., Wang, J., Engelman, A., & Cherepanov, P. (2009) · PLoS Pathogens

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 122

Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family

Wong, C. T., Xu, Y., Gupta, A., Garnett, J. A., Matthews, S. J., & Hare, S. A. (2015) · Nature Communications

Hemoglobin structure and functionEnzyme Structure and Function

Cited by 30