Petsko, Gregory A.

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Huang, Y.-H., Zhu, C., Kondo, Y., Anderson, A. C., Gandhi, A., Russell, A., Dougan, S. K., Petersen, B.-S., Melum, E., Pertel, T., et al. (2015) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

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Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson’s Disease

Schweitzer, J. S., Song, B., Herrington, T. M., Park, T.-Y., Lee, N., Ko, S., Jeon, J., Cha, Y., Kim, K., Li, Q., et al. (2020) · New England Journal of Medicine

Pluripotent Stem Cells ResearchParkinson's Disease Mechanisms and Treatments

Cited by 542

A soluble α-synuclein construct forms a dynamic tetramer

Wang, W., Perovic, I., Chittuluru, J., Kaganovich, A., Nguyen, L. T. T., Liao, J., Auclair, J. R., Johnson, D., Landeru, A., Simorellis, A. K., et al. (2011) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsProtein Structure and Dynamics

Cited by 478

Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

Intlekofer, A. M., Shih, A. H., Wang, B., Nazir, A., Rustenburg, A. S., Albanese, S. K., Patel, M., Famulare, C., Correa, F. M., Takemoto, N., et al. (2018) · Nature

Acute Myeloid Leukemia ResearchGlioma Diagnosis and Treatment

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Caspase-1 causes truncation and aggregation of the Parkinson’s disease-associated protein α-synuclein

Wang, W., Nguyen, L. T. T., Burlak, C., Chegini, F., Guo, F., Chataway, T., Ju, S., Fisher, O. S., Miller, D. W., Datta, D., et al. (2016) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 270

How Enzymes Work

Ringe, D., & Petsko, G. A. (2008) · Science

Physical Organic Chemistry and Reaction KineticsProtein Structure and Dynamics

Cited by 262

AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease

Rosenberg, J. B., Kaplitt, M. G., De, B. P., Chen, A., Flagiello, T., Salami, C., Pey, E., Zhao, L., Ricart Arbona, R. J., Monette, S., et al. (2018) · Human Gene Therapy Clinical Development

Virus-based gene therapy researchAlzheimer's disease research and treatments

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Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1

Barmada, S. J., Ju, S., Arjun, A., Batarse, A., Archbold, H. C., Peisach, D., Li, X., Zhang, Y., Tank, E. M. H., Qiu, H., et al. (2015) · Proceedings of the National Academy of Sciences

Amyotrophic Lateral Sclerosis ResearchRNA Research and Splicing

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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

Wong, M. Y., Lewis, M., Doherty, J. J., Shi, Y., Cashikar, A. G., Amelianchik, A., Tymchuk, S., Sullivan, P. M., Qian, M., Covey, D. F., et al. (2020) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 121

The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease

Qureshi, Y. H., Berman, D. E., Marsh, S. E., Klein, R. L., Patel, V. M., Simoes, S., Kannan, S., Petsko, G. A., Stevens, B., & Small, S. A. (2022) · Cell Reports

Alzheimer's disease research and treatmentsCellular transport and secretion

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