Cascio, Duilio

Engineering an allosteric transcription factor to respond to new ligands

Taylor, N. D., Garruss, A. S., Moretti, R., Chan, S., Arbing, M. A., Cascio, D., Rogers, J. K., Isaacs, F. J., Kosuri, S., Baker, D., et al. (2016) · Nature Methods

Gene Regulatory Network AnalysisMicrobial Metabolic Engineering and Bioproduction

Cited by 328

Structure-based inhibitors of amyloid beta core suggest a common interface with tau

Griner, S. L., Seidler, P., Bowler, J., Murray, K. A., Yang, T. P., Sahay, S., Sawaya, M. R., Cascio, D., Rodriguez, J. A., Philipp, S., et al. (2019) · eLife

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 121

Control of DNA minor groove width and Fis protein binding by the purine 2-amino group

Hancock, S. P., Ghane, T., Cascio, D., Rohs, R., Di Felice, R., & Johnson, R. C. (2013) · Nucleic Acids Research

DNA and Nucleic Acid ChemistryDiffusion and Search Dynamics

Cited by 83

Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples

Seidler, P. M., Boyer, D. R., Murray, K. A., Yang, T. P., Bentzel, M., Sawaya, M. R., Rosenberg, G., Cascio, D., Williams, C. K., Newell, K. L., et al. (2019) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 70

Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold

Castells-Graells, R., Meador, K., Arbing, M. A., Sawaya, M. R., Gee, M., Cascio, D., Gleave, E., Debreczeni, J. É., Breed, J., Leopold, K., et al. (2023) · Proceedings of the National Academy of Sciences

Advanced Electron Microscopy Techniques and ApplicationsEnzyme Structure and Function

Cited by 48

Comparison of two yeast MnSODs: Mitochondrial Saccharomyces cerevisiae versus cytosolic Candida albicans

Sheng, Y., Stich, T. A., Barnese, K., Gralla, E. B., Cascio, D., Britt, R. D., Cabelli, D. E., & Valentine, J. S. (2011) · Journal of the American Chemical Society

Metal-Catalyzed Oxygenation MechanismsRedox biology and oxidative stress

Cited by 43

De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

Tetreau, G., Sawaya, M. R., De Zitter, E., Andreeva, E. A., Banneville, A.-S., Schibrowsky, N. A., Coquelle, N., Brewster, A. S., Grünbein, M. L., Kovacs, G. N., et al. (2022) · Nature Communications

Enzyme Structure and FunctionInsect Resistance and Genetics

Cited by 28

De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

Tetreau, G., Sawaya, M. R., De Zitter, E., Andreeva, E. A., Banneville, A.-S., Schibrowsky, N., Coquelle, N., Brewster, A. S., Grünbein, M. L., Kovacs, G. N., et al. (2021) · Nature Communications

Enzyme Structure and FunctionInsect Resistance and Genetics

Cited by 28