Clardy, Jon

GABA-modulating bacteria of the human gut microbiota

Strandwitz, P., Kim, K. H., Terekhova, D., Liu, J. K., Sharma, A., Levering, J., McDonald, D., Dietrich, D., Ramadhar, T. R., Lekbua, A., et al. (2018) · Nature Microbiology

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 1,170

d -Amino Acids Trigger Biofilm Disassembly

Kolodkin-Gal, I., Romero, D., Cao, S., Clardy, J., Kolter, R., & Losick, R. (2010) · Science

Bacterial biofilms and quorum sensingBacterial Genetics and Biotechnology

Cited by 874

A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics

Donia, M. S., Cimermancic, P., Schulze, C. J., Wieland Brown, L. C., Martin, J., Mitreva, M., Clardy, J., Linington, R. G., & Fischbach, M. A. (2014) · Cell

Microbial Natural Products and BiosynthesisAntimicrobial Peptides and Activities

Cited by 705

Diarrhetic shellfish toxins.

Yasumoto, T., Murata, M., Oshima, Y., Sano, M., Matsumoto, G. K., & Clardy, J. (1985) · Tetrahedron

Marine Toxins and Detection MethodsMarine Sponges and Natural Products

Cited by 643

Structure of Human Methionine Aminopeptidase-2 Complexed with Fumagillin

Liu, S., Widom, J., Kemp, C. W., Crews, C. M., & Clardy, J. (1998) · Science

Enzyme Structure and FunctionPeptidase Inhibition and Analysis

Cited by 440

Akkermansia muciniphila phospholipid induces homeostatic immune responses

Bae, M., Cassilly, C. D., Liu, X., Park, S.-M., Tusi, B. K., Chen, X., Kwon, J., Filipčík, P., Bolze, A. S., Liu, Z., et al. (2022) · Nature

Immune Response and InflammationGut microbiota and health

Cited by 413

The natural history of antibiotics

Clardy, J., Fischbach, M. A., & Currie, C. R. (2009) · Current Biology

Microbial Natural Products and BiosynthesisAntibiotic Resistance in Bacteria

Cited by 402

Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes

Sinars, C. R., Cheung-Flynn, J., Rimerman, R. A., Scammell, J. G., Smith, D. F., & Clardy, J. (2003) · Proceedings of the National Academy of Sciences

Signaling Pathways in DiseaseHeat shock proteins research

Cited by 254

A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals

Alegado, R. A., Brown, L. W., Cao, S., Dermenjian, R. K., Zuzow, R., Fairclough, S. R., Clardy, J., & King, N. (2012) · eLife

Marine Invertebrate Physiology and EcologyProtist diversity and phylogeny

Cited by 249

Refined structure of the FKBP12–rapamycin–FRB ternary complex at 2.2 Å resolution

Liang, J., Choi, J., & Clardy, J. (1999) · Acta Crystallographica Section D Biological Crystallography

Signaling Pathways in DiseasePI3K/AKT/mTOR signaling in cancer

Cited by 148

Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis

Hiraki, M., Hwang, S.-Y., Cao, S., Ramadhar, T. R., Byun, S., Yoon, K. W., Lee, J. H., Chu, K., Gurkar, A. U., Kolev, V., et al. (2015) · Chemistry & Biology

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 81

The structure of leptosphaerin

Schiehser, G. A., White, J. D., Matsumoto, G., Pezzanite, J. O., & Clardy, J. (1986) · Tetrahedron Letters

Microbial Natural Products and BiosynthesisMarine Sponges and Natural Products

Cited by 49

Phytoecdysteroids of Diploclisia glaucescens Seed

Miller, R., Clardy, J., Kozlowski, J., Mikolajczak, K., Plattner, R., Powell, R., Smith, C., Weisleder, D., & Qi-Tai, Z. (1985) · Planta Medica

Phytochemical Studies and BioactivitiesPhytochemistry and Bioactive Compounds

Cited by 37