Steckelbroeck, Stephan

Human Cytosolic 3α-Hydroxysteroid Dehydrogenases of the Aldo-keto Reductase Superfamily Display Significant 3β-Hydroxysteroid Dehydrogenase Activity

Steckelbroeck, S., Jin, Y., Gopishetty, S., Oyesanmi, B., & Penning, T. M. (2004) · Journal of Biological Chemistry

Aldose Reductase and TaurineSteroid Chemistry and Biochemistry

Cited by 270

An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies

Byrns, M. C., Steckelbroeck, S., & Penning, T. M. (2008) · Biochemical Pharmacology

Aldose Reductase and TaurineBioactive Compounds and Antitumor Agents

Cited by 145

Human type 3 3α-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells

Rižner, T. L., Lin, H. K., Peehl, D. M., Steckelbroeck, S., Bauman, D. R., & Penning, T. M. (2003) · Endocrinology

Aldose Reductase and TaurineProstate Cancer Treatment and Research

Cited by 132

Identification of the Major Oxidative 3α-Hydroxysteroid Dehydrogenase in Human Prostate That Converts 5α-Androstane-3α,17β-diol to 5α-Dihydrotestosterone: A Potential Therapeutic Target for Androgen-Dependent Disease

Bauman, D. R., Steckelbroeck, S., Williams, M. V., Peehl, D. M., & Penning, T. M. (2006) · Molecular Endocrinology

Prostate Cancer Treatment and ResearchSteroid Chemistry and Biochemistry

Cited by 120

Tibolone is metabolized by the 3α/3β-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo–keto reductase 1C subfamily: inversion of stereospecificity with a Δ5(10)-3-ketosteroid

Steckelbroeck, S., Jin, Y., Oyesanmi, B., Kloosterboer, H. J., & Penning, T. M. (2004) · Molecular Pharmacology

Aldose Reductase and TaurineSteroid Chemistry and Biochemistry

Cited by 64