Seeliger, Markus A.

How Does a Drug Molecule Find Its Target Binding Site?

Shan, Y., Kim, E. T., Eastwood, M. P., Dror, R. O., Seeliger, M. A., & Shaw, D. E. (2011) · Journal of the American Chemical Society

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 614

Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms

Jura, N., Zhang, X., Endres, N. F., Seeliger, M. A., Schindler, T., & Kuriyan, J. (2011) · Molecular Cell

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 310

IFITM proteins assist cellular uptake of diverse linked chemotypes

Lou, K., Wassarman, D. R., Yang, T., Paung, Y., Zhang, Z., O’Loughlin, T. A., Moore, M. K., Egan, R. K., Greninger, P., Benes, C. H., et al. (2022) · Science

Drug Transport and Resistance MechanismsRNA Interference and Gene Delivery

Cited by 42

Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib

Leyte-Vidal, A., DeFilippis, R., Outhwaite, I. R., Kwan, I., Lee, J. Y., Leavitt, C., Miller, K. B., Rea, D., Rangwala, A. M., Lou, K., et al. (2024) · Leukemia

Chronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia Research

Cited by 17

Validation of an Allosteric Binding Site of Src Kinase Identified by Unbiased Ligand Binding Simulations

Mingione, V. R., Foda, Z. H., Paung, Y., Philipose, H., Rangwala, A. M., Shan, Y., & Seeliger, M. A. (2022) · Journal of Molecular Biology

Computational Drug Discovery MethodsProtein Structure and Dynamics

Cited by 13