Cho, Wonhwa

Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol

Liu, S.-L., Sheng, R., Jung, J. H., Wang, L., Stec, E., O'Connor, M. J., Song, S., Bikkavilli, R. K., Winn, R. A., Lee, D., et al. (2017) · Nature Chemical Biology

Lipid Membrane Structure and BehaviorCholesterol and Lipid Metabolism

Cited by 239

Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched

Zhang, Y., Bulkley, D. P., Xin, Y., Roberts, K. J., Asarnow, D. E., Sharma, A., Myers, B. R., Cho, W., Cheng, Y., & Beachy, P. A. (2018) · Cell

Hedgehog Signaling Pathway StudiesReceptor Mechanisms and Signaling

Cited by 239

Cholesterol modulates cell signaling and protein networking by specifically interacting with PDZ domain-containing scaffold proteins

Sheng, R., Chen, Y., Yung Gee, H., Stec, E., Melowic, H. R., Blatner, N. R., Tun, M. P., Kim, Y., Källberg, M., Fujiwara, T. K., et al. (2012) · Nature Communications

Lipid Membrane Structure and BehaviorCholesterol and Lipid Metabolism

Cited by 179

Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling

Sheng, R., Kim, H., Lee, H., Xin, Y., Chen, Y., Tian, W., Cui, Y., Choi, J.-C., Doh, J., Han, J.-K., et al. (2014) · Nature Communications

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

Cited by 157

Quantitative Lipid Imaging Reveals a New Signaling Function of Phosphatidylinositol-3,4-Bisphophate: Isoform- and Site-Specific Activation of Akt

Liu, S.-L., Wang, Z.-G., Hu, Y., Xin, Y., Singaram, I., Gorai, S., Zhou, X., Shim, Y., Min, J.-H., Gong, L.-W., et al. (2018) · Molecular Cell

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 141

Our evolving understanding of how 27-hydroxycholesterol influences cancer

Ma, L., Cho, W., & Nelson, E. R. (2022) · Biochemical Pharmacology

Cancer, Lipids, and MetabolismCholesterol and Lipid Metabolism

Cited by 53

Phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) specifically induces membrane penetration and deformation by Bin/amphiphysin/Rvs (BAR) domains

Yoon, Y., Zhang, X., & Cho, W. (2012) · Journal of Biological Chemistry

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 47

Lipids Regulate Lck Protein Activity through Their Interactions with the Lck Src Homology 2 Domain

Sheng, R., Jung, D.-J., Silkov, A., Kim, H., Singaram, I., Wang, Z.-G., Xin, Y., Kim, E., Park, M.-J., Thiagarajan-Rosenkranz, P., et al. (2016) · Journal of Biological Chemistry

Lipid Membrane Structure and BehaviorProtein Kinase Regulation and GTPase Signaling

Cited by 43

Cholesterol efflux protein, ABCA1, supports anticancer functions of myeloid immune cells

Bendre, S. V., Wang, Y., Hajyousif, B., K C, R., Bhogale, S. G., Pradeep, D., Krawczynska, N., Schane, C. P., Weisser, E., Singh, A., et al. (2026) · Science Advances

Immune cells in cancerCancer, Lipids, and Metabolism

Cited by 8