Sato, Shigeto

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

Matsuda, N., Sato, S., Shiba, K., Okatsu, K., Saisho, K., Gautier, C. A., Sou, Y.-S., Saiki, S., Kawajiri, S., Sato, F., et al. (2010) · Journal of Cell Biology

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

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PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

Shiba-Fukushima, K., Imai, Y., Yoshida, S., Ishihama, Y., Kanao, T., Sato, S., & Hattori, N. (2012) · Scientific Reports

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

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p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

Okatsu, K., Saisho, K., Shimanuki, M., Nakada, K., Shitara, H., Sou, Y., Kimura, M., Sato, S., Hattori, N., Komatsu, M., et al. (2010) · Genes to Cells

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

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Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice

Sato, S., Uchihara, T., Fukuda, T., Noda, S., Kondo, H., Saiki, S., Komatsu, M., Uchiyama, Y., Tanaka, K., & Hattori, N. (2018) · Scientific Reports

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

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Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease

Oji, Y., Hatano, T., Ueno, S.-I., Funayama, M., Ishikawa, K.-I., Okuzumi, A., Noda, S., Sato, S., Satake, W., Toda, T., et al. (2020) · Brain

Parkinson's Disease Mechanisms and TreatmentsLysosomal Storage Disorders Research

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