Casey, Patrick J.

Post-prenylation-processing enzymes as new targets in oncogenesis

Winter-Vann, A. M., & Casey, P. J. (2005) · Nature Reviews Cancer

Protein Kinase Regulation and GTPase SignalingCancer-related gene regulation

Cited by 357

Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf

Bergo, M. O., Gavino, B. J., Hong, C., Beigneux, A. P., McMahon, M., Casey, P. J., & Young, S. G. (2004) · Journal of Clinical Investigation

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 180

A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells

Winter-Vann, A. M., Baron, R. A., Wong, W., dela Cruz, J., York, J. D., Gooden, D. M., Bergo, M. O., Young, S. G., Toone, E. J., & Casey, P. J. (2005) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingCancer-related gene regulation

Cited by 178

Inhibition of isoprenylcysteine carboxylmethyltransferase induces autophagic-dependent apoptosis and impairs tumor growth

Wang, M., Hossain, M. S., Tan, W., Coolman, B., Zhou, J., Liu, S., & Casey, P. J. (2010) · Oncogene

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 75

Inhibition of Isoprenylcysteine Carboxylmethyltransferase Induces Cell-Cycle Arrest and Apoptosis through p21 and p21-Regulated BNIP3 Induction in Pancreatic Cancer

Manu, K. A., Chai, T. F., Teh, J. T., Zhu, W. L., Casey, P. J., & Wang, M. (2017) · Molecular Cancer Therapeutics

Pancreatic and Hepatic Oncology ResearchCancer, Lipids, and Metabolism

Cited by 55

Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal

Chai, T. F., Manu, K. A., Casey, P. J., & Wang, M. (2020) · Oncogene

Hippo pathway signaling and YAP/TAZProtein Kinase Regulation and GTPase Signaling

Cited by 20