Huisinga, Wilhelm

A Direct Approach to Conformational Dynamics Based on Hybrid Monte Carlo

Schütte, C., Fischer, A., Huisinga, W., & Deuflhard, P. (1999) · Journal of Computational Physics

Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions

Cited by 393

Development of a dosing algorithm for meropenem in critically ill patients based on a population pharmacokinetic/pharmacodynamic analysis.

Ehmann, L., Zoller, M., Minichmayr, I. K., Scharf, C., Huisinga, W., Zander, J., & Kloft, C. (2019) · International Journal of Antimicrobial Agents

Antibiotics Pharmacokinetics and EfficacyPharmaceutical studies and practices

Cited by 67

Pharmacokinetic/pharmacodynamic evaluation of hydrocortisone therapy in pediatric patients with congenital adrenal hyperplasia

Melin, J., Parra-Guillen, Z. P., Michelet, R., Truong, T., Huisinga, W., Hartung, N., Hindmarsh, P., & Kloft, C. (2020) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 34

Predicting Cortisol Exposure from Paediatric Hydrocortisone Formulation Using a Semi-Mechanistic Pharmacokinetic Model Established in Healthy Adults

Melin, J., Parra-Guillen, Z. P., Hartung, N., Huisinga, W., Ross, R. J., Whitaker, M. J., & Kloft, C. (2018) · Clinical Pharmacokinetics

Adrenal Hormones and DisordersPharmaceutical studies and practices

Cited by 17

Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach

Michelet, R., Bindellini, D., Melin, J., Neumann, U., Blankenstein, O., Huisinga, W., Johnson, T. N., Whitaker, M. J., Ross, R., & Kloft, C. (2023) · Frontiers in Pharmacology

Adrenal Hormones and DisordersPharmaceutical studies and practices

Cited by 5

A quantitative modeling framework to understand the physiology of the hypothalamic-pituitary-adrenal axis and interaction with cortisol replacement therapy

Bindellini, D., Michelet, R., Aulin, L. B. S., Melin, J., Neumann, U., Blankenstein, O., Huisinga, W., Whitaker, M. J., Ross, R., & Kloft, C. (2024) · Journal of Pharmacokinetics and Pharmacodynamics

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 4