Needham, Elise J.

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

Mills, R. J., Titmarsh, D. M., Koenig, X., Parker, B. L., Ryall, J. G., Quaife-Ryan, G. A., Voges, H. K., Hodson, M. P., Ferguson, C., Drowley, L., et al. (2017) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 478

Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway

Mills, R. J., Parker, B. L., Quaife-Ryan, G. A., Voges, H. K., Needham, E. J., Bornot, A., Ding, M., Andersson, H., Polla, M., Elliott, D. A., et al. (2019) · Cell Stem Cell

Congenital heart defects researchPluripotent Stem Cells Research

Cited by 312

Vascular cells improve functionality of human cardiac organoids

Voges, H. K., Foster, S. R., Reynolds, L., Parker, B. L., Devilée, L., Quaife-Ryan, G. A., Fortuna, P. R. J., Mathieson, E., Fitzsimmons, R., Lor, M., et al. (2023) · Cell Reports

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 139

The mitochondrial mRNA stabilizing protein, SLIRP, regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms

Sylow, L., Pham, T. C. P., Raun, S., Havula, E., Henriquez-Olguín, C., Rubalcava-Gracia, D., Frank, E., Fritzen, A., Jannig, P., Andersen, N., et al. (2024) · Nature Communications

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 19

The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms

Pham, T. C. P., Raun, S. H., Havula, E., Henriquez-Olguín, C., Rubalcava-Gracia, D., Frank, E., Fritzen, A. M., Jannig, P. R., Andersen, N. R., Kruse, R., et al. (2024) · Nature Communications

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 19

The mitochondrial mRNA stabilizing protein, SLIRP, regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms

Pham, T. C. P., Raun, S. H., Havula, E., Henriquez-Olguín, C., Rubalcava-Gracia, D., Frank, E., Fritzen, A. M., Jannig, P. R., Andersen, N. R., Kruse, R., et al. (2023) · Nature Communications

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 19