Concordet, Jean-Paul

Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR

Haeussler, M., Schönig, K., Eckert, H., Eschstruth, A., Mianné, J., Renaud, J.-B., Schneider-Maunoury, S., Shkumatava, A., Teboul, L., Kent, J., et al. (2016) · Genome biology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,756

Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1

Semenza, G. L., Jiang, B.-H., Leung, S. W., Passantino, R., Concordet, J.-P., Maire, P., & Giallongo, A. (1996) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 1,752

Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair

Auer, T. O., Duroure, K., De Cian, A., Concordet, J.-P., & Del Bene, F. (2014) · Genome Research

CRISPR and Genetic EngineeringZebrafish Biomedical Research Applications

Cited by 631

Multisite Protein Kinase A and Glycogen Synthase Kinase 3β Phosphorylation Leads to Gli3 Ubiquitination by SCF βTrCP

Tempé, D., Casas, M., Karaz, S., Blanchet-Tournier, M.-F., & Concordet, J.-P. (2006) · Molecular and Cellular Biology

Hedgehog Signaling Pathway StudiesUbiquitin and proteasome pathways

Cited by 249

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

Weber, L., Frati, G., Felix, T., Hardouin, G., Casini, A., Wollenschlaeger, C., Meneghini, V., Masson, C., De Cian, A., Chalumeau, A., et al. (2020) · Science Advances

Hemoglobinopathies and Related DisordersCRISPR and Genetic Engineering

Cited by 140

Modeling of Aniridia-Related Keratopathy by CRISPR/Cas9 Genome Editing of Human Limbal Epithelial Cells and Rescue by Recombinant PAX6 Protein

Roux, L. N., Petit, I., Domart, R., Concordet, J.-P., Qu, J., Zhou, H., Joliot, A., Ferrigno, O., & Aberdam, D. (2018) · Stem Cells

Corneal Surgery and TreatmentsOcular Disorders and Treatments

Cited by 56

Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion

Joutsen, J., Da Silva, A. J., Luoto, J. C., Budzynski, M. A., Nylund, A. S., de Thonel, A., Concordet, J.-P., Mezger, V., Sabéran-Djoneidi, D., Henriksson, E., et al. (2020) · Cell Reports

Heat shock proteins researchEndoplasmic Reticulum Stress and Disease

Cited by 51

Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina

Pulman, J., Botto, C., Malki, H., Ren, D., Oudin, P., De Cian, A., As, M., Izabelle, C., Saubamea, B., Forster, V., et al. (2024) · Molecular Therapy Nucleic Acids

CRISPR and Genetic EngineeringRetinal Development and Disorders

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