Hoehn, Kyle L.

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

Holland, W. L., Brozinick, J. T., Wang, L.-P., Hawkins, E. D., Sargent, K. M., Liu, Y., Narra, K., Hoehn, K. L., Knotts, T. A., Siesky, A., et al. (2007) · Cell Metabolism

Sphingolipid Metabolism and SignalingAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,232

Insulin resistance is a cellular antioxidant defense mechanism

Hoehn, K. L., Salmon, A. B., Hohnen-Behrens, C., Turner, N., Hoy, A. J., Maghzal, G. J., Stocker, R., Van Remmen, H., Kraegen, E. W., Cooney, G. J., et al. (2009) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 540

Excess Lipid Availability Increases Mitochondrial Fatty Acid Oxidative Capacity in Muscle

Turner, N., Bruce, C. R., Beale, S. M., Hoehn, K. L., So, T., Rolph, M. S., & Cooney, G. J. (2007) · Diabetes

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 520

Autophagy is required for exercise training‐induced skeletal muscle adaptation and improvement of physical performance

Lira, V. A., Okutsu, M., Zhang, M., Greene, N. P., Laker, R. C., Breen, D. S., Hoehn, K. L., & Yan, Z. (2013) · The FASEB Journal

Autophagy in Disease and TherapyMuscle Physiology and Disorders

Cited by 432

Regulation of Insulin Action by Ceramide

Stratford, S., Hoehn, K. L., Liu, F., & Summers, S. A. (2004) · Journal of Biological Chemistry

Sphingolipid Metabolism and SignalingMetabolism, Diabetes, and Cancer

Cited by 410

Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane

Kenwood, B. M., Weaver, J. L., Bajwa, A., Poon, I. K., Byrne, F. L., Murrow, B. A., Calderone, J. A., Huang, L., Divakaruni, A. S., Tomsig, J. L., et al. (2014) · Molecular Metabolism

Mitochondrial Function and PathologyATP Synthase and ATPases Research

Cited by 243

Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance

Fazakerley, D. J., Chaudhuri, R., Yang, P., Maghzal, G. J., Thomas, K. C., Krycer, J. R., Humphrey, S. J., Parker, B. L., Fisher-Wellman, K. H., Meoli, C. C., et al. (2018) · eLife

Coenzyme Q10 studies and effectsMitochondrial Function and Pathology

Cited by 160

Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity

Hoehn, K. L., Turner, N., Swarbrick, M. M., Wilks, D., Preston, E., Phua, Y., Joshi, H., Furler, S. M., Larance, M., Hegarty, B. D., et al. (2010) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 156

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice

Alexopoulos, S. J., Chen, S.-Y., Brandon, A. E., Salamoun, J. M., Byrne, F. L., Garcia, C. J., Beretta, M., Olzomer, E. M., Shah, D. P., Philp, A. M., et al. (2020) · Nature Communications

Adipose Tissue and MetabolismPharmacology and Obesity Treatment

Cited by 137

BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control

Axelrod, C. L., King, W. T., Davuluri, G., Noland, R. C., Hall, J., Hull, M., Dantas, W. S., Zunica, E. R., Alexopoulos, S. J., Hoehn, K. L., et al. (2020) · EMBO Molecular Medicine

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 89