Arlt, Wiebke

Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3β-hydroxysteroid dehydrogenase

Arlt, W., Auchus, R. J., & Miller, W. L. (2001) · Journal of Biological Chemistry

Ovarian function and disordersAdrenal Hormones and Disorders

Cited by 157

Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement

Chortis, V., Taylor, A. E., Schneider, P., Tomlinson, J. W., Hughes, B. A., O'Neil, D. M., Libé, R., Allolio, B., Bertagna, X., Bertherat, J., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism

Adrenal and Paraganglionic TumorsAdrenal Hormones and Disorders

Cited by 154

Outcome of Cushing's disease following transsphenoidal surgery in a single center over 20 years

Hassan-Smith, Z. K., Sherlock, M., Reulen, R. C., Arlt, W., Ayuk, J., Toogood, A. A., Cooper, M. S., Johnson, A. P., & Stewart, P. M. (2012) · The Journal of Clinical Endocrinology & Metabolism

Pituitary Gland Disorders and TreatmentsMeningioma and schwannoma management

Cited by 153

Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol

Woods, C. P., Argese, N., Chapman, M., Boot, C., Webster, R., Dabhi, V., Grossman, A. B., Toogood, A. A., Arlt, W., Stewart, P. M., et al. (2015) · European Journal of Endocrinology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 152

Diagnosis of endocrine disease: The diagnostic performance of adrenal biopsy: a systematic review and meta-analysis

Bancos, I., Tamhane, S., Shah, M., Delivanis, D. A., Alahdab, F., Arlt, W., Fassnacht, M., & Murad, M. H. (2016) · European Journal of Endocrinology

Adrenal and Paraganglionic TumorsAdrenal Hormones and Disorders

Cited by 144

A new dawn for androgens: novel lessons from 11-oxygenated C19 steroids

Pretorius, E., Arlt, W., & Storbeck, K.-H. (2017) · Molecular and Cellular Endocrinology

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 142

Steroid Metabolome Analysis in Disorders of Adrenal Steroid Biosynthesis and Metabolism

Storbeck, K.-H., Schiffer, L., Baranowski, E. S., Chortis, V., Prete, A., Barnard, L., Gilligan, L. C., Taylor, A. E., Idkowiak, J., Arlt, W., et al. (2019) · Endocrine Reviews

Adrenal Hormones and DisordersMetabolism and Genetic Disorders

Cited by 141

CT characteristics of pheochromocytoma: relevance for the evaluation of adrenal incidentaloma

Canu, L., Van Hemert, J. A. W., Kerstens, M. N., Hartman, R. P., Khanna, A., Kraljevic, I., Kastelan, D., Badiu, C., Ambroziak, U., Tabarin, A., et al. (2019) · The Journal of Clinical Endocrinology & Metabolism

Adrenal and Paraganglionic TumorsNeuroendocrine Tumor Research Advances

Cited by 131

Congenital adrenal hyperplasia and P450 oxidoreductase deficiency

Krone, N., Dhir, V., Ivison, H. E., & Arlt, W. (2007) · Clinical Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 131

Comorbidities in mild autonomous cortisol secretion and the effect of treatment: systematic review and meta-analysis

Pelsma, I. C. M., Fassnacht, M., Tsagarakis, S., Terzolo, M., Tabarin, A., Sahdev, A., Newell-Price, J., Marina, L., Lorenz, K., Bancos, I., et al. (2023) · European Journal of Endocrinology

Adrenal and Paraganglionic TumorsAdrenal Hormones and Disorders

Cited by 130

Salivary Cortisone Reflects Cortisol Exposure Under Physiological Conditions and After Hydrocortisone

Debono, M., Harrison, R. F., Whitaker, M. J., Eckland, D., Arlt, W., Keevil, B. G., & Ross, R. J. (2016) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 128

A pharmacokinetic and pharmacodynamic study of delayed‐ and extended‐release hydrocortisone (Chronocort TM ) vs. conventional hydrocortisone (Cortef TM ) in the treatment of congenital adrenal hyperplasia

Verma, S., VanRyzin, C., Sinaii, N., Kim, M. S., Nieman, L. K., Ravindran, S., Calis, K. A., Arlt, W., Ross, R. J., & Merke, D. P. (2010) · Clinical Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 126

Approach to the patient: the adult with congenital adrenal hyperplasia

Auchus, R. J., & Arlt, W. (2013) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 121

An oral multiparticulate, modified‐release, hydrocortisone replacement therapy that provides physiological cortisol exposure

Whitaker, M. J., Debono, M., Huatan, H., Merke, D. P., Arlt, W., & Ross, R. J. (2014) · Clinical Endocrinology

Adrenal Hormones and DisordersAdvanced Drug Delivery Systems

Cited by 121

Genotype-phenotype correlation in 153 adult patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency: analysis of the United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) cohort

Krone, N., Rose, I. T., Willis, D. S., Hodson, J., Wild, S. H., Doherty, E. J., Hahner, S., Parajes, S., Stimson, R. H., Han, T. S., et al. (2013) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 119

Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality

Bancos, I., Hazeldine, J., Chortis, V., Hampson, P., Taylor, A. E., Lord, J. M., & Arlt, W. (2017) · European Journal of Endocrinology

Adrenal Hormones and DisordersImmune Cell Function and Interaction

Cited by 110

Increased 5α-Reductase Activity and Adrenocortical Drive in Women with Polycystic Ovary Syndrome

Vassiliadi, D. A., Barber, T. M., Hughes, B. A., McCarthy, M. I., Wass, J. A. H., Franks, S., Nightingale, P., Tomlinson, J. W., Arlt, W., & Stewart, P. M. (2009) · The Journal of Clinical Endocrinology & Metabolism

Ovarian function and disordersAdrenal Hormones and Disorders

Cited by 110

Modified-Release Hydrocortisone in Congenital Adrenal Hyperplasia

Merke, D. P., Mallappa, A., Arlt, W., Brac de la Perriere, A., Lindén Hirschberg, A., Juul, A., Newell-Price, J., Perry, C. G., Prete, A., Rees, D. A., et al. (2021) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 109

ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of adrenal insufficiency

Arlt, W., Baldeweg, S. E., Pearce, S. H. S., & Simpson, H. L. (2020) · European Journal of Endocrinology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 107

Prenatal diagnosis of P450 oxidoreductase deficiency (ORD): a disorder causing low pregnancy estriol, maternal and fetal virilization, and the Antley-Bixler syndrome phenotype

Shackleton, C., Marcos, J., Arlt, W., & Hauffa, B. P. (2004) · American Journal of Medical Genetics Part A

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 104

A missense mutation in the human cytochrome b5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency

Idkowiak, J., Randell, T., Dhir, V., Patel, P., Shackleton, C. H. L., Taylor, N. F., Krone, N., & Arlt, W. (2012) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 104

Treatment and health outcomes in adults with congenital adrenal hyperplasia

Han, T. S., Walker, B. R., Arlt, W., & Ross, R. J. (2014) · Nature Reviews Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 102

Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species

Arlt, W., Martens, J. W. M., Song, M., Wang, J. T., Auchus, R. J., & Miller, W. L. (2002) · Endocrinology

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 101

SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute adrenal insufficiency (adrenal crisis) in adult patients

Arlt, W., & _, _. (2016) · Endocrine Connections

Adrenal Hormones and DisordersElectrolyte and hormonal disorders

Cited by 101