Meharena, Hiruy S.

Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity

Victor, M. B., Leary, N., Luna, X., Meharena, H. S., Scannail, A. N., Bozzelli, P. L., Samaan, G., Murdock, M. H., von Maydell, D., Effenberger, A. H., et al. (2022) · Cell Stem Cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 316

Lipid Accumulation Induced by APOE4 Impairs Microglial Surveillance of Neuronal-Network Activity

Victor, M. B., Leary, N., Luna, X., Meharena, H. S., Bozzelli, P. L., Samaan, G., Murdock, M. H., von Maydell, D., Effenberger, A. H., Cerit, O., et al. (2022) · Cell stem cell

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 311

Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble

Marco, A., Meharena, H. S., Dileep, V., Raju, R. M., Davila-Velderrain, J., Zhang, A. L., Adaikkan, C., Young, J. Z., Gao, F., Kellis, M., et al. (2020) · Nature Neuroscience

Memory and Neural MechanismsGenomics and Chromatin Dynamics

Cited by 159

Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration

Dileep, V., Boix, C. A., Mathys, H., Marco, A., Welch, G. M., Meharena, H. S., Loon, A., Jeloka, R., Peng, Z., Bennett, D. A., et al. (2023) · Cell

DNA Repair MechanismsAlzheimer's disease research and treatments

Cited by 130

Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors

Meharena, H. S., Marco, A., Dileep, V., Lockshin, E. R., Akatsu, G. Y., Mullahoo, J., Watson, L. A., Ko, T., Guerin, L. N., Abdurrob, F., et al. (2022) · Cell Stem Cell

Down syndrome and intellectual disability researchTelomeres, Telomerase, and Senescence

Cited by 92