Felsher, Dean W.

MYC regulates the antitumor immune response through CD47 and PD-L1

Casey, S. C., Tong, L., Li, Y., Do, R., Walz, S., Fitzgerald, K. N., Gouw, A. M., Baylot, V., Gütgemann, I., Eilers, M., et al. (2016) · Science

Cancer Immunotherapy and BiomarkersPhagocytosis and Immune Regulation

Cited by 1,403

MYC as a regulator of ribosome biogenesis and protein synthesis

van Riggelen, J., Yetil, A., & Felsher, D. W. (2010) · Nature Reviews Cancer

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 956

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

Shachaf, C. M., Kopelman, A. M., Arvanitis, C., Karlsson, Å., Beer, S., Mandl, S., Bachmann, M. H., Borowsky, A. D., Ruebner, B., Cardiff, R. D., et al. (2004) · Nature

Cancer Cells and MetastasisHepatocellular Carcinoma Treatment and Prognosis

Cited by 874

NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis

Ma, C., Kesarwala, A. H., Eggert, T., Medina-Echeverz, J., Kleiner, D. E., Jin, P., Stroncek, D. F., Terabe, M., Kapoor, V., ElGindi, M., et al. (2016) · Nature

Liver Disease Diagnosis and TreatmentCancer, Lipids, and Metabolism

Cited by 766

HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo

Gao, P., Zhang, H., Dinavahi, R., Li, F., Xiang, Y., Raman, V., Bhujwalla, Z. M., Felsher, D. W., Cheng, L., Pevsner, J., et al. (2007) · Cancer Cell

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

Cited by 523

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis

Xiang, Y., Stine, Z. E., Xia, J., Lu, Y., O’Connor, R. S., Altman, B. J., Hsieh, A. L., Gouw, A. M., Thomas, A. G., Gao, P., et al. (2015) · Journal of Clinical Investigation

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 409

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma

Miess, H., Dankworth, B., Gouw, A. M., Rosenfeldt, M., Schmitz, W., Jiang, M., Saunders, B., Howell, M., Downward, J., Felsher, D. W., et al. (2018) · Oncogene

Ferroptosis and cancer prognosisCancer, Hypoxia, and Metabolism

Cited by 361

CD4+ T Cells Contribute to the Remodeling of the Microenvironment Required for Sustained Tumor Regression upon Oncogene Inactivation

Rakhra, K., Bachireddy, P., Zabuawala, T., Zeiser, R., Xu, L., Kopelman, A., Fan, A. C., Yang, Q., Braunstein, L., Crosby, E., et al. (2010) · Cancer Cell

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 339

c-Myc Is a Critical Target for C/EBPα in Granulopoiesis

Johansen, L. M., Iwama, A., Lodie, T. A., Sasaki, K., Felsher, D. W., Golub, T. R., & Tenen, D. G. (2001) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 263

MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism

Shroff, E. H., Eberlin, L. S., Dang, V. M., Gouw, A. M., Gabay, M., Adam, S. J., Bellovin, D. I., Tran, P. T., Philbrick, W. M., Garcia-Ocana, A., et al. (2015) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

Cited by 255

Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression

Beverly, L. J., Felsher, D. W., & Capobianco, A. J. (2005) · Cancer Research

Cancer-related Molecular PathwaysDevelopmental Biology and Gene Regulation

Cited by 157

Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription

Struntz, N. B., Chen, A., Deutzmann, A., Wilson, R. M., Stefan, E., Evans, H. L., Ramirez, M. A., Liang, T., Caballero, F., Wildschut, M. H. E., et al. (2019) · Cell Chemical Biology

Chemical Synthesis and AnalysisCancer-related Molecular Pathways

Cited by 130

MYC Regulates the HIF2α Stemness Pathway via Nanog and Sox2 to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells

Das, B., Pal, B., Bhuyan, R., Li, H., Sarma, A., Gayan, S., Talukdar, J., Sandhya, S., Bhuyan, S., Gogoi, G., et al. (2019) · Cancer Research

Cancer Cells and MetastasisHematopoietic Stem Cell Transplantation

Cited by 92

O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis

Taparra, K., Wang, H., Malek, R., Lafargue, A., Barbhuiya, M. A., Wang, X., Simons, B. W., Ballew, M., Nugent, K., Groves, J., et al. (2018) · Journal of Clinical Investigation

Glycosylation and Glycoproteins ResearchCancer, Hypoxia, and Metabolism

Cited by 80