Lee, Ho-Joon

Cysteine depletion induces pancreatic tumor ferroptosis in mice

Badgley, M. A., Kremer, D. M., Maurer, H. C., DelGiorno, K. E., Lee, H.-J., Purohit, V., Sagalovskiy, I. R., Ma, A., Kapilian, J., Firl, C. E. M., et al. (2020) · Science

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 1,294

Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer

Halbrook, C. J., Pontious, C., Kovalenko, I., Lapienyte, L., Dreyer, S., Lee, H.-J., Thurston, G., Zhang, Y., Lazarus, J., Sajjakulnukit, P., et al. (2019) · Cell Metabolism

Immune cells in cancerPancreatic and Hepatic Oncology Research

Cited by 419

Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis

Zhang, Y., Lazarus, J., Steele, N. G., Yan, W., Lee, H.-J., Nwosu, Z. C., Halbrook, C. J., Menjivar, R. E., Kemp, S. B., Sirihorachai, V. R., et al. (2020) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchTGF-β signaling in diseases

Cited by 385

Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway

Boyer, S., Lee, H.-J., Steele, N., Zhang, L., Sajjakulnukit, P., Andren, A., Ward, M. H., Singh, R., Basrur, V., Zhang, Y., et al. (2022) · eLife

Immune cells in cancerPancreatic and Hepatic Oncology Research

Cited by 56

Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma

Xu, J., Reznik, E., Lee, H.-J., Gundem, G., Jonsson, P., Sarungbam, J., Bialik, A., Sanchez-Vega, F., Creighton, C. J., Hoekstra, J., et al. (2019) · eLife

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

Cited by 43

Metabolic signatures of regulation by phosphorylation and acetylation

Smith, K., Shen, F., Lee, H. J., & Chandrasekaran, S. (2019) · iScience

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 20