Sette, Alessandro

Precursors of human CD4 + cytotoxic T lymphocytes identified by single-cell transcriptome analysis

Patil, V. S., Madrigal, A., Schmiedel, B. J., Clarke, J., O’Rourke, P., de Silva, A. D., Harris, E., Peters, B., Seumois, G., Weiskopf, D., et al. (2018) · Science Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 262

Cross-reactive memory T cells and herd immunity to SARS-CoV-2

Lipsitch, M., Grad, Y. H., Sette, A., & Crotty, S. (2020) · Nature Reviews Immunology

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 260

Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools

Greenbaum, J. A., Andersen, P. H., Blythe, M., Bui, H., Cachau, R. E., Crowe, J., Davies, M., Kolaskar, A. S., Lund, O., Morrison, S., et al. (2007) · Journal of Molecular Recognition

vaccines and immunoinformatics approachesMachine Learning in Bioinformatics

Cited by 244

Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals

Lederer, K., Parvathaneni, K., Painter, M. M., Bettini, E., Agarwal, D., Lundgreen, K. A., Weirick, M., Goel, R. R., Xu, X., Drapeau, E. M., et al. (2021) · Cell

SARS-CoV-2 and COVID-19 ResearchT-cell and B-cell Immunology

Cited by 179

Selective CD4+ T Cell Help for Antibody Responses to a Large Viral Pathogen: Deterministic Linkage of Specificities

Sette, A., Moutaftsi, M., Moyron-Quiroz, J., McCausland, M. M., Davies, D. H., Johnston, R. J., Peters, B., Rafii-El-Idrissi Benhnia, M., Hoffmann, J., Su, H.-P., et al. (2008) · Immunity

T-cell and B-cell Immunologyvaccines and immunoinformatics approaches

Cited by 168

Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs

Weingarten-Gabbay, S., Klaeger, S., Sarkizova, S., Pearlman, L. R., Chen, D.-Y., Gallagher, K. M. E., Bauer, M. R., Taylor, H. B., Dunn, W. A., Tarr, C., et al. (2021) · Cell

vaccines and immunoinformatics approachesSARS-CoV-2 and COVID-19 Research

Cited by 147

17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells

Schmiedel, B. J., Seumois, G., Samaniego-Castruita, D., Cayford, J., Schulten, V., Chavez, L., Ay, F., Sette, A., Peters, B., & Vijayanand, P. (2016) · Nature Communications

Asthma and respiratory diseasesGenomics and Chromatin Dynamics

Cited by 127

Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection

Painter, M. M., Johnston, T. S., Lundgreen, K. A., Santos, J. J. S., Qin, J. S., Goel, R. R., Apostolidis, S. A., Mathew, D., Fulmer, B., Williams, J. C., et al. (2023) · Nature Immunology

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 106

Immunodominance changes as a function of the infecting dengue virus serotype and primary versus secondary infection

Weiskopf, D., Angelo, M. A., Sidney, J., Peters, B., Shresta, S., & Sette, A. (2014) · Journal of Virology

Mosquito-borne diseases and controlvaccines and immunoinformatics approaches

Cited by 90

Cross-presentation of caspase-cleaved apoptotic self antigens in HIV infection

Rawson, P. M., Molette, C., Videtta, M., Altieri, L., Franceschini, D., Donato, T., Finocchi, L., Propato, A., Paroli, M., Meloni, F., et al. (2007) · Nature Medicine

HIV Research and TreatmentImmunotherapy and Immune Responses

Cited by 86

Cellular immune response to cryptic epitopes during therapeutic gene transfer

Li, C., Goudy, K., Hirsch, M., Asokan, A., Fan, Y., Alexander, J., Sun, J., Monahan, P., Seiber, D., Sidney, J., et al. (2009) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 79

Epitope specific antibodies and T cell receptors in the immune epitope database

Mahajan, S., Vita, R., Shackelford, D., Lane, J., Schulten, V., Zarebski, L., Jespersen, M. C., Marcatili, P., Nielsen, M., Sette, A., et al. (2018) · Frontiers in Immunology

vaccines and immunoinformatics approachesT-cell and B-cell Immunology

Cited by 53

Customized versus universal scoring functions

Logean, A., Sette, A., & Rognan, D. (2001) · Bioorganic & Medicinal Chemistry Letters

Computational Drug Discovery Methodsvaccines and immunoinformatics approaches

Cited by 46

The role of immune-mediated alterations and disorders in ALS disease

Rodrigues Lima-Junior, J., Sulzer, D., Lindestam Arlehamn, C. S., & Sette, A. (2021) · Human Immunology

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 33

T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity

Sagan, S. A., Moinfar, Z., Moseley, C. E., Dandekar, R., Spencer, C. M., Verkman, A. S., Ottersen, O. P., Sobel, R. A., Sidney, J., Sette, A., et al. (2023) · Proceedings of the National Academy of Sciences

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 25

Thioamide Analogues of MHC I Antigen Peptides

Gibadullin, R., Morris, R. K., Niu, J., Sidney, J., Sette, A., & Gellman, S. H. (2023) · Journal of the American Chemical Society

Chemical Synthesis and Analysisvaccines and immunoinformatics approaches

Cited by 17

β-amino acid substitution in the SIINFEKL antigen alters immunological recognition

Rastogi, I., Mannone, J. A., Gibadullin, R., Moseman, J. E., Sidney, J., Sette, A., McNeel, D. G., & Gellman, S. H. (2025) · Cancer Biology & Therapy

Immunotherapy and Immune ResponsesChemical Synthesis and Analysis

Cited by 5