Friedman, Clayton E.

Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation

Friedman, C. E., Nguyen, Q., Lukowski, S. W., Helfer, A., Chiu, H. S., Miklas, J., Levy, S., Suo, S., Han, J.-D. J., Osteil, P., et al. (2018) · Cell Stem Cell

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 258

Vascular cells improve functionality of human cardiac organoids

Voges, H. K., Foster, S. R., Reynolds, L., Parker, B. L., Devilée, L., Quaife-Ryan, G. A., Fortuna, P. R. J., Mathieson, E., Fitzsimmons, R., Lor, M., et al. (2023) · Cell Reports

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 139

Multiplexed Functional Assessments of MYH7 Variants in Human Cardiomyocytes

Friedman, C. E., Fayer, S., Pendyala, S., Chien, W.-M., Loiben, A., Tran, L., Chao, L. S., McKinstry, A., Ahmed, D., Farris, S. D., et al. (2024) · Circulation: Genomic and Precision Medicine

Cardiomyopathy and Myosin StudiesGenomics and Rare Diseases

Cited by 17

Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects

Pendyala, S., Partington, K., Bradley, N., McEwen, A. E., Straub, G., Kim, H.-J., Fayer, S., Holmes, D. L., Sitko, K. A., Garge, R. K., et al. (2026) · Cell

Genomics and Rare DiseasesNuclear Structure and Function

Cited by 10

Editing stem cell genomes at scale to measure variant effects in diverse cell and genetic contexts

Fayer, S., Garge, R. K., Hopkins, M., Friedman, C. E., McGee, A. V., Rico, J., Powell, R. L., McDermot, E., Smith, N. T., Pendyala, S., et al. (2025) · medRxiv

CRISPR and Genetic EngineeringGenomics and Rare Diseases

Cited by 4