Fukuto, Jon M.

Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

Ida, T., Sawa, T., Ihara, H., Tsuchiya, Y., Watanabe, Y., Kumagai, Y., Suematsu, M., Motohashi, H., Fujii, S., Matsunaga, T., et al. (2014) · Proceedings of the National Academy of Sciences

Sulfur Compounds in BiologyRedox biology and oxidative stress

Cited by 934

Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine

Ignarro, L. J., Fukuto, J. M., Griscavage, J. M., Rogers, N. E., & Byrns, R. E. (1993) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 856

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: Implications of their possible biological activity and utility

Ono, K., Akaike, T., Sawa, T., Kumagai, Y., Wink, D. A., Tantillo, D. J., Hobbs, A. J., Nagy, P., Xian, M., Lin, J., et al. (2014) · Free Radical Biology and Medicine

Sulfur Compounds in BiologyRedox biology and oxidative stress

Cited by 422

Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species

Fukuto, J. M., Carrington, S. J., Tantillo, D. J., Harrison, J. G., Ignarro, L. J., Freeman, B. A., Chen, A., & Wink, D. A. (2012) · Chemical Research in Toxicology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 389

Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Wong, P. S.-Y., Hyun, J., Fukuto, J. M., Shirota, F. N., DeMaster, E. G., Shoeman, D. W., & Nagasawa, H. T. (1998) · Biochemistry

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 363

The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations

Ridnour, L. A., Thomas, D. D., Mancardi, D., Espey, M. G., Miranda, K. M., Paolocci, N., Feelisch, M., Fukuto, J., & Wink, D. A. (2004) · Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 312

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system

Miranda, K. M., Paolocci, N., Katori, T., Thomas, D. D., Ford, E., Bartberger, M. D., Espey, M. G., Kass, D. A., Feelisch, M., Fukuto, J. M., et al. (2003) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 283

The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway

Kapil, V., Khambata, R. S., Jones, D. A., Rathod, K., Primus, C., Massimo, G., Fukuto, J. M., & Ahluwalia, A. (2020) · Pharmacological Reviews

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 248

Formation of free nitric oxide from l-arginine by nitric oxide synthase-direct enhancement of generation by superoxide dismutase

Hobbs, A. J., Fukuto, J. M., & Ignarro, L. J. (1994) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 244

The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal

Forman, H. J., Fukuto, J. M., Miller, T., Zhang, H., Rinna, A., & Levy, S. (2008) · Archives of Biochemistry and Biophysics

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 226

The reaction of H2S with oxidized thiols: generation of persulfides and implications to H2S biology

Francoleon, N. E., Carrington, S. J., & Fukuto, J. M. (2011) · Archives of Biochemistry and Biophysics

Sulfur Compounds in BiologyRedox biology and oxidative stress

Cited by 199

Signaling and stress: The redox landscape in NOS2 biology

Thomas, D. D., Heinecke, J. L., Ridnour, L. A., Cheng, R. Y., Kesarwala, A. H., Switzer, C. H., McVicar, D. W., Roberts, D. D., Glynn, S., Fukuto, J. M., et al. (2015) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 150

Conversion of nitroxyl (HNO) to nitric oxide (NO) in biological systems-the role of physiological oxidants and relevance to the biological activity of HNO

Fukuto, J. M., Hobbs, A. J., & Ignarro, L. J. (1993) · Biochemical and Biophysical Research Communications

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 147

The pharmacological activity of nitroxyl: a potent vasodilator with activity similar to nitric oxide and/or endothelium-derived relaxing factor

Fukuto, J. M., Chiang, K., Hszieh, R., Wong, P., & Chaudhuri, G. (1992) · The Journal of Pharmacology and Experimental Therapeutics

Nitric Oxide and Endothelin EffectsEicosanoids and Hypertension Pharmacology

Cited by 143

Chemical oxidation of N-hydroxyguanidine compounds

Fukuto, J. M., Wallace, G. C., Hszieh, R., & Chaudhuri, G. (1992) · Biochemical Pharmacology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 113

Discriminating formation of HNO from other reactive nitrogen oxide species

Donzelli, S., Espey, M. G., Thomas, D. D., Mancardi, D., Tocchetti, C. G., Ridnour, L. A., Paolocci, N., King, S. B., Miranda, K. M., Lazzarino, G., et al. (2006) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 112

Comparing the chemical biology of NO and HNO

Flores-Santana, W., Switzer, C., Ridnour, L. A., Basudhar, D., Mancardi, D., Donzelli, S., Thomas, D. D., Miranda, K. M., Fukuto, J. M., & Wink, D. A. (2009) · Archives of Pharmacal Research

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 50

Nitrite-Dependent Nitric Oxide Production Pathway: Diversity of NO Production Systems

Yamasaki, H., Watanabe, N. S., Fukuto, J., & Cohen, M. F. (2014) · Oxidative Stress in Applied Basic Research and Clinical Practice

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 10