Opitz, Christiane A.

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

Opitz, C. A., Litzenburger, U. M., Sahm, F., Ott, M., Tritschler, I., Trump, S., Schumacher, T., Jestaedt, L., Schrenk, D., Weller, M., et al. (2011) · Nature

Tryptophan and brain disordersToxic Organic Pollutants Impact

Cited by 1,898

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

Platten, M., Nollen, E. A. A., Röhrig, U. F., Fallarino, F., & Opitz, C. A. (2019) · Nature Reviews Drug Discovery

Tryptophan and brain disordersAmino Acid Enzymes and Metabolism

Cited by 1,586

Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts

Makarenko, I., Opitz, C. A., Leake, M. C., Neagoe, C., Kulke, M., Gwathmey, J. K., del Monte, F., Hajjar, R. J., & Linke, W. A. (2004) · Circulation Research

Cardiomyopathy and Myosin StudiesCardiac Fibrosis and Remodeling

Cited by 332

The therapeutic potential of targeting tryptophan catabolism in cancer

Opitz, C. A., Somarribas Patterson, L. F., Mohapatra, S. R., Dewi, D. L., Sadik, A., Platten, M., & Trump, S. (2020) · British Journal of Cancer

Cancer Immunotherapy and BiomarkersTryptophan and brain disorders

Cited by 300

The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas

Sonner, J. K., Deumelandt, K., Ott, M., Thomé, C. M., Rauschenbach, K. J., Schulz, S., Munteanu, B., Mohapatra, S., Adam, I., Hofer, A.-C., et al. (2016) · OncoImmunology

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 64