Stegmaier, Kimberly
Broad Institute · Harvard University · Dana-Farber/Boston Children's Cancer and Blood Disorders Center
14 papers on CoChatORCID 0000-0003-0218-7895
Most cited papers
- Verified
Mutational heterogeneity in cancer and the search for new cancer-associated genes
Lawrence, M. S., Stojanov, P., Polak, P., Kryukov, G. V., Cibulskis, K., Sivachenko, A., Carter, S. L., Stewart, C., Mermel, C. H., Roberts, S. A., et al. (2013) · Nature
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 5,461
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Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells
Meyers, R. M., Bryan, J. G., McFarland, J. M., Weir, B. A., Sizemore, A. E., Xu, H., Dharia, N. V., Montgomery, P. G., Cowley, G. S., Pantel, S., et al. (2017) · Nature Genetics
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 1,952
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Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules
Nabet, B., Ferguson, F. M., Seong, B. K. A., Kuljanin, M., Leggett, A. L., Mohardt, M. L., Robichaud, A., Conway, A. S., Buckley, D. L., Mancias, J. D., et al. (2020) · Nature Communications
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 312
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The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice
Townsend, E. C., Murakami, M. A., Christodoulou, A., Christie, A. L., Köster, J., DeSouza, T. A., Morgan, E. A., Kallgren, S. P., Liu, H., Wu, S.-C., et al. (2016) · Cancer Cell
Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research
Cited by 295
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Multicenter Feasibility Study of Tumor Molecular Profiling to Inform Therapeutic Decisions in Advanced Pediatric Solid Tumors: The Individualized Cancer Therapy (iCat) Study
Harris, M. H., DuBois, S. G., Glade Bender, J. L., Kim, A., Crompton, B. D., Parker, E., Dumont, I. P., Hong, A. L., Guo, D., Church, A., et al. (2016) · JAMA Oncology
Cancer Genomics and DiagnosticsGenomics and Rare Diseases
Cited by 206
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EWS/FLI confers tumor cell synthetic lethality to CDK12 inhibition in Ewing sarcoma
Iniguez, A. B., Stolte, B., Wang, E. J., Conway, A. S., Alexe, G., Dharia, N. V., Kwiatkowski, N., Zhang, T., Abraham, B. J., Mora, J., et al. (2018) · Cancer Cell
Sarcoma Diagnosis and TreatmentPARP inhibition in cancer therapy
Cited by 173
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A first-generation pediatric cancer dependency map
Dharia, N. V., Kugener, G., Guenther, L. M., Malone, C. F., Durbin, A. D., Hong, A. L., Howard, T. P., Bandopadhayay, P., Wechsler, C. S., Fung, I., et al. (2021) · Nature Genetics
Cancer Genomics and DiagnosticsCRISPR and Genetic Engineering
Cited by 153
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Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group
Shulman, D. S., Klega, K., Imamovic-Tuco, A., Clapp, A., Nag, A., Thorner, A. R., Van Allen, E., Ha, G., Lessnick, S. L., Gorlick, R., et al. (2018) · British Journal of Cancer
Sarcoma Diagnosis and TreatmentCancer Genomics and Diagnostics
Cited by 149
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Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism.
Schauer, N. J., Liu, X., Magin, R. S., Doherty, L. M., Chan, W. C., Ficarro, S. B., Hu, W., Roberts, R. M., Iacob, R. E., Stolte, B., et al. (2020) · Scientific Reports
Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways
Cited by 125
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The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia
Banerji, V., Frumm, S. M., Ross, K. N., Li, L. S., Schinzel, A. C., Hahn, C. K., Kakoza, R. M., Chow, K. T., Ross, L., Alexe, G., et al. (2012) · Journal of Clinical Investigation
Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes
Cited by 105
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The public repository of xenografts enables discovery and randomized phase II-like trials in mice
Townsend, E. C., Murakami, M. A., Christodoulou, A., Christie, A. L., Köster, J., DeSouza, T. A., Morgan, E. A., Kallgren, S. P., Liu, H., Wu, S.-C., et al. (2016) · Cancer Cell
Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research
Cited by 80
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VRK1 as a synthetic lethal target in VRK2 promoter-methylated cancers of the nervous system
So, J., Mabe, N. W., Englinger, B., Chow, K.-H., Moyer, S. M., Yerrum, S., Trissal, M. C., Marques, J. G., Kwon, J. J., Shim, B., et al. (2022) · JCI Insight
Glioma Diagnosis and TreatmentChromatin Remodeling and Cancer
Cited by 45
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The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy
Liu, S., Marneth, A. E., Alexe, G., Walker, S. R., Gandler, H. I., Ye, D. Q., Labella, K., Mathur, R., Toniolo, P. A., Tillgren, M., et al. (2018) · Blood Advances
Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes
Cited by 33
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A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia
Harada, T., Heshmati, Y., Kalfon, J., Ferrucio, J. X., Perez, M., Ewers, J., Kossenkov, A., Ellegast, J. M., Yi, J. S., Bowker, A., et al. (2021) · Genes & Development
Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics
Cited by 31
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