Sousa, Alexander A.
Broad Institute · Howard Hughes Medical Institute · Harvard University
5 papers on CoChatORCID 0000-0001-8533-391X
Most cited papers
- Verified
Search-and-replace genome editing without double-strand breaks or donor DNA
Anzalone, A. V., Randolph, P. B., Davis, J. R., Sousa, A. A., Koblan, L. W., Levy, J. M., Chen, P. J., Wilson, C., Newby, G. A., Raguram, A., et al. (2019) · Nature
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 4,767
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Enhanced proofreading governs CRISPR-Cas9 targeting accuracy
Chen, J. S., Dagdas, Y. S., Kleinstiver, B. P., Welch, M. M., Sousa, A. A., Harrington, L. B., Sternberg, S. H., Joung, J. K., Yildiz, A., & Doudna, J. A. (2017) · Nature
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,168
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High levels of AAV vector integration into CRISPR-induced DNA breaks
Hanlon, K. S., Kleinstiver, B. P., Garcia, S. P., Zaborowski, M. P., Volak, A., Spirig, S. E., Muller, A., Sousa, A. A., Tsai, S. Q., Bengtsson, N. E., et al. (2019) · Nature Communications
Virus-based gene therapy researchCRISPR and Genetic Engineering
Cited by 431
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Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs
Listgarten, J., Weinstein, M., Kleinstiver, B. P., Sousa, A. A., Joung, J. K., Crawford, J., Gao, K., Hoang, L., Elibol, M., Doench, J. G., et al. (2018) · Nature Biomedical Engineering
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 336
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Designing and executing prime editing experiments in mammalian cells
Doman, J. L., Sousa, A. A., Randolph, P. B., Chen, P. J., & Liu, D. R. (2022) · Nature Protocols
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 172
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