Chen, Qingfeng

Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer

Kumar, V., Ramnarayanan, K., Sundar, R., Padmanabhan, N., Srivastava, S., Koiwa, M., Yasuda, T., Koh, V., Huang, K. K., Tay, S. T., et al. (2022) · Cancer Discovery

Single-cell and spatial transcriptomicsGastric Cancer Management and Outcomes

Cited by 573

Interaction between tumour‐infiltrating B cells and T cells controls the progression of hepatocellular carcinoma

Garnelo, M., Tan, A., Her, Z., Yeong, J., Lim, C. J., Chen, J., Lim, K. H., Weber, A., Chow, P., Chung, A., et al. (2017) · Gut

Cancer Immunotherapy and BiomarkersHepatocellular Carcinoma Treatment and Prognosis

Cited by 461

Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations

Loh, K. M., Ang, L. T., Zhang, J., Kumar, V., Ang, J., Auyeong, J. Q., Lee, K. L., Choo, S. H., Lim, C. Y. Y., Nichane, M., et al. (2014) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 418

A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

Ang, L. T., Tan, A. K. Y., Autio, M. I., Goh, S. H., Choo, S. H., Lee, K. L., Tan, J., Pan, B., Lee, J. J. H., Lum, J. J., et al. (2018) · Cell Reports

Pluripotent Stem Cells ResearchLiver physiology and pathology

Cited by 220

Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy

Ma, S., Zhao, Y., Lee, W. C., Ong, L.-T., Lee, P. L., Jiang, Z., Oguz, G., Niu, Z., Liu, M., Goh, J. Y., et al. (2022) · Nature Communications

Cancer Immunotherapy and BiomarkersCancer, Hypoxia, and Metabolism

Cited by 200

Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy

Zhao, Y., Shuen, T. W. H., Toh, T. B., Chan, X. Y., Liu, M., Tan, S. Y., Fan, Y., Yang, H., Lyer, S. G., Bonney, G. K., et al. (2018) · Gut

Cancer Immunotherapy and BiomarkersHepatocellular Carcinoma Treatment and Prognosis

Cited by 200

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses

Chong, S. Z., Evrard, M., Devi, S., Chen, J., Lim, J. Y., See, P., Zhang, Y., Adrover, J. M., Lee, B., Tan, L., et al. (2016) · Journal of Experimental Medicine

Chemokine receptors and signalingImmune cells in cancer

Cited by 142

Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

Hong, X., Nguyen, H. T., Chen, Q., Zhang, R., Hagman, Z., Voorhoeve, P. M., & Cohen, S. M. (2014) · The EMBO Journal

Hippo pathway signaling and YAP/TAZProtein Kinase Regulation and GTPase Signaling

Cited by 121

Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease

Tan-Garcia, A., Wai, L.-E., Zheng, D., Ceccarello, E., Jo, J., Banu, N., Khakpoor, A., Chia, A., Tham, C. Y. L., Tan, A. T., et al. (2017) · Journal of Hepatology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 68

Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma

Ang, D. A., Carter, J.-M., Deka, K., Tan, J. H. L., Zhou, J., Chen, Q., Chng, W. J., Harmston, N., & Li, Y. (2024) · Nature Communications

Multiple Myeloma Research and TreatmentsNF-κB Signaling Pathways

Cited by 13

Humanized mouse as a tool to predict immunotoxicity of human biologics

Yong, K. S. M., Her, Z., Tan, S. Y., Tan, W. W. S., Liu, M., Lai, F., Heng, S. M., Fan, Y., Chang, K. T. E., Wang, C.-I., et al. (2020) · Frontiers in Immunology

Immunotoxicology and immune responsesAnimal testing and alternatives

Cited by 13