Malech, Harry L.

Chronic Granulomatous Disease: Report on a National Registry of 368 Patients

Winkelstein, J. A., Marino, M. C., Johnston, R. B., Boyle, J., Curnutte, J., Gallin, J. I., Malech, H. L., Holland, S. M., Ochs, H., Quie, P., et al. (2000) · Medicine

Immunodeficiency and Autoimmune DisordersNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 1,728

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

Lood, C., Blanco, L. P., Purmalek, M. M., Carmona-Rivera, C., De Ravin, S. S., Smith, C. K., Malech, H. L., Ledbetter, J. A., Elkon, K. B., & Kaplan, M. J. (2016) · Nature Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsSystemic Lupus Erythematosus Research

Cited by 1,570

Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease

Kuhns, D. B., Alvord, W. G., Heller, T., Feld, J. J., Pike, K. M., Marciano, B. E., Uzel, G., DeRavin, S. S., Priel, D. A. L., Soule, B. P., et al. (2010) · New England Journal of Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 568

Differentiation of human and murine induced pluripotent stem cells to microglia-like cells

Pandya, H., Shen, M. J., Ichikawa, D. M., Sedlock, A. B., Choi, Y., Johnson, K. R., Kim, G., Brown, M. A., Elkahloun, A. G., Maric, D., et al. (2017) · Nature Neuroscience

Pluripotent Stem Cells ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 405

Cloning of a 67-kD Neutrophil Oxidase Factor with Similarity to a Noncatalytic Region of p60 c-src

Leto, T. L., Lomax, K. J., Volpp, B. D., Nunoi, H., Sechler, J. M. G., Nauseef, W. M., Clark, R. A., Gallin, J. I., & Malech, H. L. (1990) · Science

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 386

Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1

Mamcarz, E., Zhou, S., Lockey, T., Abdelsamed, H., Cross, S. J., Kang, G., Ma, Z., Condori, J., Dowdy, J., Triplett, B., et al. (2019) · New England Journal of Medicine

Virus-based gene therapy researchImmunodeficiency and Autoimmune Disorders

Cited by 263

CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease

De Ravin, S. S., Li, L., Wu, X., Choi, U., Allen, C., Koontz, S., Lee, J., Theobald-Whiting, N., Chu, J., Garofalo, M., et al. (2017) · Science Translational Medicine

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 258

Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease

De Ravin, S. S., Reik, A., Liu, P.-Q., Li, L., Wu, X., Su, L., Raley, C., Theobald, N., Choi, U., Song, A. H., et al. (2016) · Nature Biotechnology

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 195

Induction of the respiratory burst in HL-60 cells. Correlation of function and protein expression.

Levy, R., Rotrosen, D., Nagauker, O., Leto, T. L., & Malech, H. L. (1990) · The Journal of Immunology

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 131

A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human T cells

Zhou, S., Mody, D., DeRavin, S. S., Hauer, J., Lu, T., Ma, Z., Hacein-Bey Abina, S., Gray, J. T., Greene, M. R., Cavazzana-Calvo, M., et al. (2010) · Blood

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 119

Enhancers Are Major Targets for Murine Leukemia Virus Vector Integration

De Ravin, S. S., Su, L., Theobald, N., Choi, U., Macpherson, J. L., Poidinger, M., Symonds, G., Pond, S. M., Ferris, A. L., Hughes, S. H., et al. (2014) · Journal of Virology

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 103